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English, Sciences, 1 season, 44 episodes, 10 hours, 5 minutes
About
Lan-Lan Smith, Editor-in-Chief of The Lancet Haematology, and the journal’s authors explore their research and its impact on people’s health, health care, and health policy in this regular podcast.
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Banu Aygun on sickle cell anaemia

Professor Banu Aygun joins us to discuss the REACH trial testing hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00078-4?dgcid=buzzsprout_icw_podcast_generic_lanhaeContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
5/23/202411 minutes, 13 seconds
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Sabine Braat and Katherine Fielding on haemoglobin thresholds to define anaemia

Dr Sabine Braat and Dr Katherine Fielding join us to discuss their study presenting new haemoglobin thresholds for defining anaemia.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00030-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhaeContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
3/1/202418 minutes, 6 seconds
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Elisabeth Schorb on the MARTA phase 2 trial

Doctor Elisabeth Schorb joins us to discuss the MARTA phase 2 trial, treating older, fit patients with primary diffuse large B-cell CNS lymphoma with high-dose chemotherapy and autologous stem-cell transplantation.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00371-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhaeContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
2/29/20249 minutes, 23 seconds
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Stephan Ehl on paediatric autoimmune lymphoproliferative immunodeficiencies

Professor Stephan Ehl joins us to discuss a prospective observational study on paediatric autoimmune lymphoproliferative immunodeficiencies.Read the full article:https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00638-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanoncContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
1/31/202413 minutes, 3 seconds
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Dr Susan O'Brien on the PREVAPIX-ALL trial

Dr Susan O'Brien joins Lan-Lan Smith to discuss results of the phase 3 PREVAPIX-ALL trial, which compares direct oral anticoagulant apixaban to low-molecular-weight-heparin for the prevention of venous thromboembolism in children with newly diagnosed acute lymphoblastic leukaemia or lymphoma.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00314-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhaeContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
12/20/202313 minutes, 50 seconds
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Enrico Lopriore on haemolytic disease of the fetus and newborn

Professor Enrico Lopriore joins us to discuss a trial testing darbepoetin alfa to prevent postnatal anaemia in infants with haemolytic disease of the fetus and newborn.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00285-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhaeContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
11/29/202312 minutes, 33 seconds
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Meletios Dimopoulos on relapsed and refractory multiple myeloma

Professor Meletios Dimopoulos joins us to discuss two trials for patients with relapsed and refractory multiple myeloma - the first report of the DREAMM-3 phase 3 and long-term follow-up of the APOLLO phase 3 trial.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00243-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhaeContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
10/3/202311 minutes
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Eric Ohuma on haemoglobin concentrations and neonatal outcomes

Dr Eric Ohuma joins us to tell us about a study recently published in The Lancet Haematology on the association between maternal haemoglobin concentrations and maternal and neonatal outcomes.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00170-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhaeContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
8/29/202316 minutes, 27 seconds
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Margaret Ragni on tranexamic acid to treat heavy menstrual bleeding

Professor Margaret Ragni joins us to discuss the VWDMin study, published in The Lancet Haematology. In this phase 3, randomised, crossover trial, recombinant von Willebrand factor and tranexamic acid are used to treat heavy menstrual bleeding in patients with mild and moderate von Willebrand disease in the USA. Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00119-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhaeContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
7/31/202313 minutes, 13 seconds
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Oreofe Odejide and Thomas Kuczmarski on mental health and lymphoma

Dr Odejide and Dr Kuczmarski tell us about a study recently published in The Lancet Haematology on the effect of pre-existing mental health conditions on survival in patients with diffuse large B-cell lymphoma.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00094-7/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae
7/3/202316 minutes, 32 seconds
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Alok Srivastava on fitusiran for patients with haemophilia A and B

Professor Alok Srivastava tells us about two clinical trials being published in The Lancet and The Lancet Haematology on a new siRNA therapy called fitusiran for patients with haemophilia A and B.Read the two trials:Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH)https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00284-2/fulltext?dgcid=buzzsprout_icw_podcast_buzzsprout_generalFitusiran prophylaxis in people with severe haemophilia A or haemophilia B without inhibitors (ATLAS-A/B)https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00037-6/fulltext?dgcid=buzzsprout_icw_podcast_buzzsprout_general
3/29/202318 minutes, 41 seconds
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Emmanuela E Ambrose on stroke prevention in children with sickle cell disease

Dr Emmanuela E Ambrose tells us about the SPHERE trial on hydroxyurea dose escalation for primary stroke prevention in children with sickle cell disease in TanzaniaRead the full article:Hydroxyurea with dose escalation for primary stroke risk reduction in children with sickle cell anaemia in Tanzania (SPHERE)
3/2/202311 minutes, 31 seconds
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Sumit Gupta on racial and ethnic disparities in leukaemia survival outcomes

Dr Sumit Gupta discusses how racial and ethnic disparities affect survival outcomes of children and young adults with acute lymphocytic leukaemia.Read the full article:Racial and ethnic disparities in childhood and young adult acute lymphocytic leukaemia
1/30/202322 minutes, 10 seconds
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Xiao-Jun Huang on cellular therapy in China

Professor Xiao-Jun Huang discusses this Lancet Haematology series on Cellular Therapy in China, covering the history, current research challenges, and future of HSCT and CAR T-cell therapies in China.Read the Series papers:Cellular therapy in China
11/28/202228 minutes, 10 seconds
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Glenn Pierce on haemophilia care in LMICs

Dr Glenn Pierce discusses the World Federation of Hemophilia’s Humanitarian Aid Program which provides access to haemophilia care in low-income and lower-middle-income countries.Read the full Review:Achieving access to haemophilia care in low-income and lower-middle-income countries
8/30/202234 minutes, 55 seconds
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Amy DeZern on the link between myelodysplastic syndrome and autoimmune disorders

Dr Amy DeZern discusses the link between myelodysplastic syndrome and autoimmune disorders and the need for a multidisciplinary approach for the treatment of patients who have both.Read the full article:Myelodysplastic syndrome and autoimmune disorders: two sides of the same coin?
6/30/202212 minutes, 50 seconds
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Nicholas Crombie and Gavin Perkins on resuscitation with blood products compared with saline

Dr Nicholas Crombie and Professor Gavin Perkins discuss their randomised phase 3 trial in which they investigated resuscitation with blood products compared with saline in patients with trauma-related haemorrhagic shock receiving prehospital care. 
3/7/202215 minutes, 5 seconds
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Fredrik Schjesvold on OCEAN phase 3

Dr Fredrik Schjesvold discusses the results of the OCEAN phase 3 trial testing melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide. Read the full article:Melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide (OCEAN)
1/31/202212 minutes, 24 seconds
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Jacob D Soumerai and Andrew D Zelenetz on the BOVen regimen for previously untreated patients with chronic lymphocytic leukaemia

Dr Jacob D Soumerai and Prof Andrew D Zelenetz discuss their phase 2 trial of the BOVen regimen and MRD-driven treatment discontinuation in previously untreated patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00307-0/fulltext 
11/25/202111 minutes, 59 seconds
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Raul Cordoba on haematological malignancies in older people

Dr Raul Cordoba discusses the joint Series between The Lancet Healthy Longevity and The Lancet Haematology on haematological malignancies in older people.Read the full article:A comprehensive approach to therapy of haematological malignancies in older patients
11/3/202116 minutes, 24 seconds
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Obiageli Nnodu and Dennis Chao on child mortality from sickle cell disease in Nigeria

Professor Obiageli Nnodu and Dr Dennis Chao join acting Deputy Editor Emma Cookson to talk about their new study describing modelling of child mortality as a result of sickle cell disease in Nigeria. Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00191-5/fulltext
9/21/20219 minutes, 3 seconds
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Zuguo Mei and Gary Brittenham on iron deficiency

Senior Assistant Editor Ben Burwood speaks with Dr Zuguo Mei (Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA)  and Dr Gary M Brittenham (Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY, USA) about their work defining physiologically based serum ferritin thresholds for iron deficiency.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00168-X/fulltext
7/27/20218 minutes, 34 seconds
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Eugenia Trigoso Arjona (in English) on nursing and haematological care

To mark International Nurses Day, Eugenia Trigoso Arjona, nurse coordinator at Hospital La Fe (Valencia, Spain) and chair of the European Society for Blood and Marrow Transplantation Nurses Global Education Committee, joins acting Editor-in-Chief Yaiza del Pozo Martin to discuss how nurses can reshape the future of haematological care. 
5/11/202128 minutes, 34 seconds
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Eugenia Trigoso Arjona (in Spanish) on nursing and haematological care

Para el Día International de la Enfermera, Eugenia Trigoso Arjona, enfermera coordinadora en el Hospital La Fe (Valencia, España) y presidenta del comité de educación de la European Society for Blood and Marrow Transplantation Nurses hablo con la Editora Yaiza del Pozo Martin sobre como las enfermeras pueden remodelar el futuro de la hematología. 
5/11/202129 minutes, 11 seconds
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Nada Hamad on inclusion and diversity in haematology

A/Prof Nada Hamad (St Vincent’s hospital, Sydney, Australia) joins Editor-in-Chief Dr Lan-Lan Smith to discuss inclusion and diversity in haematology-oncology and transplantation.  
2/23/202130 minutes, 2 seconds
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Dr Judith Boer on lymphoblastic leukaemia in children

Editor-in-Chief, Dr Lan-Lan Smith, speaks with Dr Judith Boer (Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands) about outcome of ABL-class acute lymphoblastic leukaemia in children in the pre-tyrosine kinase inhibitor era.Read the full article:https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(20)30353-7/fulltext
12/22/202010 minutes, 24 seconds
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Imatinib for paediatric leukaemia

Andrea Biondi joins The Lancet Haematology to discuss his work on imatinib as a treatment for paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia.
12/15/20188 minutes, 33 seconds
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Predicting the risk of adenoviraemia

Prashant Hiwarkar joins The Lancet Haematology to discuss his new paper, an investigation into whether serial faecal PCR monitoring can predict the risk of adenoviraemia and survival outcomes after HSCT.
8/31/20184 minutes, 51 seconds
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Adverse events in haematological malignancies

Lead author Gita Thanarajasingam joins The Lancet Haematology to discuss the new Commission on assessment and adverse event reporting in haematological malignancies.
6/12/201812 minutes, 31 seconds
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EPO blood doping and cycling: The Lancet Haematology: June 29, 2017

Jules Heuberger talks about his study on the effectiveness of EPO use by cyclists.
6/30/20178 minutes, 34 seconds
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Trauma-induced coagulopathy: The Lancet Haematology: June issue

Petra Innerhofer discusses reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma.
6/3/20179 minutes, 10 seconds
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Childhood leukaemia survival (CONCORD-2): The Lancet Haematology: April 11, 2017

Audrey Bonaventure discusses her CONCORD-2 study, monitoring survival trends of two types of childhood leukaemia in 53 countries between 1995 and 2009.
4/12/20175 minutes, 46 seconds
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Superficial-vein thrombosis: The Lancet Haematology: February 15 2017

Jan Beyer discusses the SURPRISE trial of patients developing complications from superficial-vein thrombosis.
2/16/201710 minutes, 27 seconds
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Economic burden of blood disorders in Europe: The Lancet Haematology: July 21, 2016

Dr Jose Leal discusses a study of the costs related to malignant and non-malignant blood disorders in Europe in 2012.
7/21/20169 minutes, 32 seconds
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Castleman disease: The Lancet Haematology: March 17, 2016

David Fajgenbaum discusses a literature review to raise awareness of idiopathic multicentric Castleman disease, a poorly understood haematological disorder.
3/18/201617 minutes, 14 seconds
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Deep-vein thrombosis: The Lancet Haematology, October 29, 2015

Walter Ageno discusses the use of an algorithm combining limited and whole-leg compression ultrasonography to diagnose deep-vein thrombosis.
10/30/20158 minutes, 23 seconds
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Financial toxicity: The Lancet Haematology: September 17, 2015

Scott Huntington discusses the financial toxicity of oncology treatments
9/17/20156 minutes, 6 seconds
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Idiopathic thrombocytopenic purpura: The Lancet Haematology: July 29, 2015

James Bussel discusses a study looking at treatment options for children facing idiopathic thrombocytopenic purpura.
7/29/20156 minutes, 24 seconds
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INWORKS: The Lancet Haematology: June 29, 2015

Klervi Leuraud discusses a study reporting on the risk of developing leukaemia and lymphoma in workers monitored for radiation exposure.
6/29/20156 minutes, 36 seconds
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Warfarin: The Lancet Haematology: May 26, 2015

Páll Önundarson describes a new method for monitoring clotting in patients treated with warfarin, which they tested in a non-inferiority, randomised clinical trial.
5/26/201512 minutes, 5 seconds
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Atrial fibrillation and NOACs: The Lancet Haematology: April 2, 2015

Mahmoud Zureik discusses risk of bleeding in patients with non-valvular atrial fibrillation who switched and those who remained on a vitamin K antagonist.
4/2/20159 minutes, 12 seconds
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1 million stem cells: The Lancet Haematology: February 27, 2015

Dietger Niederwieser and Richard Lane discuss the journey to 1 million haematopoietic stem cell transplantations.
2/27/201513 minutes, 20 seconds
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The Lancet Haematology: January 7, 2015

Guillermo Garcia-Manero discusses a phase 1/2 study on sequential azacitidine and lenalidomide in high-risk MDS and AML.
1/7/201510 minutes, 14 seconds
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The Lancet Haematology: December 1, 2014

Gregory Kato discusses a phase I study for the treatment of leg ulcers for people with sickle-cell disease.
12/2/201411 minutes, 2 seconds