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Psychopharmacology and Psychiatry Updates

English, Health / Medicine, 1 season, 213 episodes, 1 day, 15 hours, 2 minutes
About
Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from CME presentations. Practical and free of commercial bias. Not sponsored by any pharmaceutical company.
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CBD in Psychiatry: Promise or Hype?

In this episode, we explore the potential uses of Cannabidiol (CBD) in psychiatric practice. We discuss its mechanisms, evidence for various disorders, and guidelines for safe use. Is CBD the next breakthrough in mental health treatment, or just another passing trend? Faculty: David Mischoulon, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Natural Medication in Psychiatry: Focus on Versatile Agents and Combination Strategies Cannabidiol: Evidence for Psychiatric Disorders and Recommendations for Using It
10/23/20249 minutes, 37 seconds
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Beyond Dopamine: Cannabidiol in Parkinson's Care

In this episode, we explore the use of medical cannabis in treating Parkinson's disease. We discuss a retrospective study that reveals promising results for both motor and non-motor symptoms. Could medical cannabis be the versatile solution we've been seeking for Parkinson's treatment? Faculty: Gregory Pontone, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 59 Medical Cannabis in the Treatment of Parkinson’s Disease
10/18/20248 minutes, 56 seconds
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Is NAC Promising in Bipolar and Depression Treatment?

In this episode, we explore the potential of N-acetylcysteine (NAC) in treating mood disorders. We discuss its mechanism of action, clinical evidence for its use in depression and bipolar disorder, and its possible benefits for both adults and children. Could this natural compound revolutionize our approach to mood stabilization? Faculty: David Mischoulon, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Natural Medication in Psychiatry: Focus on Versatile Agents and Combination Strategies Exploring the Evidence of N-Acetyl-Cysteine (NAC) for Mood Disorders
10/13/20247 minutes, 58 seconds
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Microbes and the Mind: Probiotics and ADHD

In this episode, we explore the potential use of probiotics in treating ADHD symptoms in children and adolescents. Could the gut microbiome hold the key to managing this complex neurodevelopmental disorder? We discuss a recent meta-analysis and its implications for future research and clinical practice. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 19 Efficacy of Probiotics in Treating ADHD Symptoms
10/8/20249 minutes, 48 seconds
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Lithium, Lamotrigine, and Labor: Managing Bipolar Disorder in Expectant Mothers

In this episode, we explore the challenges and best practices for managing bipolar disorder during pregnancy. We discuss key medications, their risks and benefits, and the importance of individualized treatment plans. How do we balance maternal mental health with fetal safety when treating bipolar disorder in pregnant women? Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Perinatal Treatment of Bipolar Disorder Guiding Principles for Treating Bipolar Disorder During Pregnancy
10/3/20249 minutes, 32 seconds
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Rethinking Haloperidol in Geriatric Delirium

In this episode, we explore a recent study challenging the safety concerns surrounding haloperidol use in older patients post-surgery. We discuss its implications for managing delirium and compare it to other antipsychotics. Could haloperidol be the unsung hero in our psychopharmacological arsenal? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 59 Comparative Safety of Oral Antipsychotics for Adverse Events in Adults After Surgery
9/28/202412 minutes, 10 seconds
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Antipsychotics in Pregnancy: A Balancing Act

In this episode, we explore the use of atypical antipsychotics during pregnancy for women with bipolar disorder. We discuss recent research findings, potential risks, and the delicate balance between managing maternal mental health and fetal safety. How do clinicians approach this challenging clinical decision? Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Perinatal Treatment of Bipolar Disorder Risks of Using Antipsychotics During Pregnancy
9/23/20247 minutes, 34 seconds
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Risperidone in Youth Anorexia: A Promising Solution?

In this episode, we explore the use of risperidone in treating anorexia nervosa in children and adolescents. We discuss a groundbreaking study examining its efficacy and tolerability. Can atypical antipsychotics like risperidone offer hope for young anorexia patients, or are we still searching for effective pharmacological treatments? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CME: CAP Smart Takes Vol. 18 Efficacy of Risperidone as Treatment for Anorexia Nervosa
9/18/202411 minutes, 26 seconds
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Navigating Lithium: A Guide for Expectant Mothers with Bipolar Disorder

In this episode, we explore the complexities of managing lithium during pregnancy for women with bipolar disorder. How do lithium levels change throughout pregnancy, and what monitoring is necessary? We discuss dosing strategies, fetal monitoring, and postpartum considerations to ensure the best outcomes for both mother and baby. Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Perinatal Treatment of Bipolar Disorder Bipolar Disorder During Pregnancy: Management of Lithium
9/13/20249 minutes, 28 seconds
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DORA: A New Frontier in Insomnia Treatment

In this episode, we explore the revolutionary potential of daridorexant, a new dual orexin receptor antagonist (DORA) for treating chronic insomnia. We discuss its unique mechanism of action, efficacy, and implications for future insomnia treatment. Could this medication be the key to "turning off" wakefulness in stubborn cases of insomnia? Faculty: Carlos H. Schenck, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 58 Use of Daridorexant for the Management of Chronic Insomnia
9/8/202411 minutes, 21 seconds
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Debunking Myths: Lithium Use in Pregnancy

In this episode, we explore the risks and benefits of using lithium during pregnancy for women with bipolar disorder. We discuss recent research on cardiac malformations and dose-dependent risks. Is the fear of lithium use in pregnancy justified by the latest evidence? Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Perinatal Treatment of Bipolar Disorder Risks of Using Lithium in Pregnancy
9/3/202410 minutes, 47 seconds
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SSRIs and Kids: Escitalopram for Pediatric Anxiety

In this episode, we explore a groundbreaking study on escitalopram's efficacy in treating generalized anxiety disorder in children and adolescents. We discuss its potential as the first FDA-approved medication for youth anxiety. How might this change our approach to pediatric anxiety treatment? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 18 The Role of Escitalopram in Treating Generalized Anxiety Disorder in Youth
8/29/202411 minutes, 47 seconds
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Unraveling Treatment Resistance: A Psychodynamic Approach

In this episode, we explore psychodynamic psychopharmacology and its role in addressing treatment-resistant cases. We discuss how patient-doctor relationships, transference, and countertransference can impact medication effectiveness. How might your own unconscious biases influence your prescribing decisions? Faculty: David Mintz, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.75 CME: Psychodynamic Psychopharmacology: From Biomedical Approaches to Patient Relationships Cultivating a Therapeutic Alliance
8/24/202413 minutes, 34 seconds
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Psychedelics: A New Frontier in Psychiatry

In this episode, we explore the therapeutic potential of psychedelic compounds in psychiatry. We discuss their definition, mechanism of action, and potential uses in treating anxiety and depression. How might psychedelics reshape the future of psychopharmacology? Faculty: Sidney LeFay, D.O. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 58 Psychedelics as Transformative Therapeutics
8/19/202410 minutes, 53 seconds
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Beyond the Prescription Pad: Navigating Patient Ambivalence

In this episode, we explore the concept of patient ambivalence in psychopharmacology. How can understanding a patient's conflicting feelings about treatment improve outcomes? We discuss strategies for recognizing and addressing ambivalence, and its impact on medication adherence and effectiveness. Faculty: David Mintz, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.75 CME: Psychodynamic Psychopharmacology: From Biomedical Approaches to Patient Relationships Attending the Patient’s Ambivalence
8/14/202412 minutes, 9 seconds
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Unplugging from Vaping: Cessation Strategies for Teens

In this episode, we explore vaping cessation methods used by US adolescent e-cigarette users. We discuss a study analyzing the prevalence and effectiveness of various quitting strategies, considering factors like demographics and perception of harm. How can healthcare providers tailor their approach to help teens quit vaping? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 17 Adoption of Vaping Cessation Methods by U.S. Adolescents
8/9/202410 minutes, 53 seconds
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When Drugs Don't Work: A Psychodynamic Approach

In this episode, we explore Psychodynamic Psychopharmacology, an innovative approach to treating medication-resistant patients. We discuss how psychological factors influence drug responses and learn techniques to enhance treatment outcomes. Could understanding the meaning patients attach to their medications be the key to unlocking treatment resistance? Faculty: David Mintz, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.75 CME: Psychodynamic Psychopharmacology: From Biomedical Approaches to Patient Relationships An Introduction to Psychodynamic Psychopharmacology
8/4/202411 minutes, 12 seconds
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Rethinking Rx: Benzodiazepines and Suicide Risk

In this episode, we explore the complex relationship between benzodiazepine use and suicide risk, examining a groundbreaking French study that challenges our understanding of this connection. Is our go-to anxiety treatment potentially increasing suicide risk? Faculty: Paul Zarkowski, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 57 Risk for Suicide Attempts and Suicide Associated With Benzodiazepines
7/30/20249 minutes, 43 seconds
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The Psychology of Prescribing: Optimizing Outcomes Through Understanding

In this episode, we explore how a psychodynamic approach can shed light on treatment-resistant cases. Can understanding a patient's psychological dynamics be the key to unlocking better outcomes? Faculty: David Mintz, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.75 CME: Psychodynamic Psychopharmacology: From Biomedical Approaches to Patient Relationships Understanding the Problem of Treatment Resistance
7/25/202414 minutes, 36 seconds
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ADHD and Pain: A Surprising Link

In this episode, we explore the fascinating connection between ADHD, pain sensitivity, and methylphenidate treatment in children. Could methylphenidate help reduce pain sensitivity in pediatric ADHD patients? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 17 Effect of Methylphenidate on Pain Perception Thresholds in Children With ADHD
7/20/202411 minutes, 59 seconds
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Restoring Rest: Insomnia Interventions for Depressed Patients

In this episode, we dive into the complex world of treating insomnia in patients with major depressive disorder. What's the best approach to help these patients find restful sleep and improve their mood? Join us as we explore a range of strategies, from medication to behavioral interventions. Faculty: Amit Chopra, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Navigating Insomnia in Major Depressive Disorder: Advances in Management Treatment Strategies for Managing Insomnia in MDD
7/15/202415 minutes, 8 seconds
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Restoring Sleep in Major Depression: Orexin, Melatonin, and More

In this episode, we explore the latest pharmacologic interventions for managing insomnia in patients with major depressive disorder. Can dual orexin receptor antagonists, melatonin agonists, and low-dose doxepin provide relief for those struggling with sleep? Join us as we discuss the advances in treating insomnia and depression. Faculty: Amit Chopra, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CMEs: Navigating Insomnia in Major Depressive Disorder: Advances in Management Other Pharmacologic Interventions for Insomnia
7/10/202410 minutes, 51 seconds
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Enhancing Pediatric Depression Treatment: The Role of Fish Oil and CBT

In this episode, we explore the potential of fish oil as an adjunct to cognitive–behavioral therapy for treating depression in youth. Can this combination enhance treatment outcomes, or is cognitive–behavioral therapy alone just as effective? Join us as we dive into this intriguing study. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 16 Is Fish Oil Effective in Youth Depression?
7/5/202411 minutes, 38 seconds
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Pharmacological Strategies for Insomnia in MDD

In this episode, we explore the use of benzodiazepines and nonbenzodiazepine hypnotics for managing insomnia in major depressive disorder. How do these medications work, and what are the key considerations when prescribing them? Join us as we navigate the complexities of pharmacologic interventions for insomnia. Faculty: Amit Chopra, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Navigating Insomnia in Major Depressive Disorder: Advances in Management Pharmacologic Interventions for Insomnia: Benzodiazepines and Non-Benzodiazepine Hypnotics
6/30/202412 minutes, 6 seconds
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Balancing Benefits and Risks: Antipsychotics in Hepatic Dysfunction

In this episode, we explore the safety of antipsychotics in patients with liver disease. How can psychiatrists navigate the risk–benefit balance when treating medically complex individuals? Dr. Sydney LeFay discusses key insights from a recent review article, guiding antipsychotic selection and monitoring. Faculty: Sydney LeFay, D.O. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 56 Antipsychotic Safety in Liver Disease
6/25/202411 minutes, 10 seconds
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Insomnia and Depression: A Tangled Web

In this episode, we explore the complex relationship between insomnia and major depressive disorder. How does insomnia impact the course and treatment of depression? Join us as we dive into the neurobiology and clinical implications of this fascinating topic with expert Dr. Amit Chopra. Faculty: Amit Chopra, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Navigating Insomnia in Major Depressive Disorder: Advances in Management Understanding the Relationship Between Insomnia Disorder and MDD
6/20/202416 minutes, 1 second
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ADHD Treatment During Pregnancy: Insights from Denmark

In this episode, we explore the long-term effects of ADHD medication use during pregnancy on children's development. Can continuing treatment pose risks, or is it safer than previously thought? Join us as we dive into a groundbreaking Danish study that sheds light on this critical question. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 16 In Utero Exposure to ADHD Medication and Long-Term Offspring Outcomes
6/15/20249 minutes, 19 seconds
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The Power of Nonpharmacologic Therapies in Fibromyalgia

In this episode, we explore the growing evidence for nonpharmacologic therapies in managing fibromyalgia symptoms. Could a combination of exercise, cognitive–behavioral therapy, and integrative approaches, like acupuncture or yoga, be the key to better outcomes for patients resistant to traditional treatments? Faculty: Daniel Clauw, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Nociplastic Pain Syndromes: Focus on Fibromyalgia Nonpharmacologic Therapies for Fibromyalgia
6/10/20248 minutes, 52 seconds
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Highlights From APA 2024: Key Insights on Psychopharmacology

In this episode, the editorial team of the Psychopharmacology Institute discusses 3 important topics presented at the APA Annual Meeting: Prescribing psychiatric medications during pregnancy, recent advances in clozapine treatment, and managing eating disorders, namely anorexia nervosa and bulimia nervosa. The episode covers the safety and dose adjustments for medications like SSRIs, lamotrigine, and lithium during pregnancy; early initiation and monitoring of clozapine; and effective treatments, including psychotherapy, olanzapine, and fluoxetine for eating disorders. Hosts: Flavio Guzman, M.D., Paz Badia, M.D., and Lorena Rodriguez, M.D.  
6/5/202418 minutes, 17 seconds
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Antidepressants in Pregnancy: Weighing the Evidence

In this episode, we discuss a new study on maternal depression, antidepressant use, and pregnancy complications. Can antidepressants during pregnancy harm the baby? Dr. Lauren Osborne helps us weigh the risks and benefits. Faculty: Lauren Osborne, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 56 Neonatal and Pregnancy Complications Following Maternal Depression or Antidepressant Exposure
5/31/202411 minutes, 24 seconds
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Unraveling the Pharmacological Puzzle of Fibromyalgia

In this episode, we explore the most effective pharmacologic treatments for fibromyalgia, a complex nociplastic pain syndrome. Dr. Daniel Clauw shares his insights on the top drug classes for managing fibromyalgia and discusses why opioids should be avoided. Could the hyperactive endogenous opioid system in fibromyalgia patients explain the ineffectiveness of opioids? Faculty: Daniel Claw, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Nociplastic Pain Syndromes: Focus on Fibromyalgia Pharmacologic Therapies for Fibromyalgia
5/26/20248 minutes, 16 seconds
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Weighing the Evidence: Antipsychotics in Pediatric Anorexia Nervosa

In this episode, we explore the use of antipsychotic medication in treating children and adolescents with anorexia nervosa. Can these medications play a role in promoting weight gain and reducing comorbid symptoms? Or do the risks outweigh the potential benefits in this vulnerable population? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CME: CAP Smart Takes Vol. 15 Antipsychotics in the Treatment of Youth With Anorexia Nervosa
5/21/202412 minutes, 22 seconds
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Beyond the Pain: Diagnosing Fibromyalgia

In this episode, we dive into the diagnosis of fibromyalgia, a common nociplastic pain syndrome. We explore how to assess widespread pain and associated symptoms and how to understand fibromyalgia as a spectrum rather than a binary diagnosis. How can this nuanced approach help us tailor treatment strategies?  Faculty: Daniel Clauw, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Nociplastic Pain Syndromes: Focus on Fibromyalgia Diagnosing Fibromyalgia
5/17/20247 minutes, 16 seconds
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Informed Consent and SSRIs: Discussing the Risk of Irreversible Sexual Side Effects

In this episode, we delve into the potential for irreversible sexual dysfunction after SSRI use, based on a large-scale Israeli study. Could a few months or even days of antidepressant treatment lead to permanent erectile issues? Faculty: Paul Zarkowski, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 55 Risk of Irreversible Post‑SSRI Sexual Dysfunction With Antidepressants
5/11/20249 minutes, 52 seconds
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Mastering Clozapine: Adverse Effect Management

In this episode, we discuss the management of common adverse effects associated with clozapine treatment, including myocarditis, cardiomyopathy, tachycardia, orthostatic hypotension, and metabolic syndrome. How can clinicians mitigate these risks while optimizing treatment outcomes for patients with treatment-resistant schizophrenia? Faculty: Brian Miller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Clozapine: Management and Challenges Managing Cardiac and Metabolic Adverse Effects of Clozapine
5/6/202415 minutes, 27 seconds
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Preventing Depression and Anxiety Relapse in Youth

In this episode, we explore relapse prevention strategies for youth with depression and anxiety disorders. Are there effective ways to reduce the risk and prolong the time to relapse? Dr. David Rosenberg discusses the findings of a recent meta-analysis and systematic review on this crucial topic. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 15 Relapse Prevention Strategies for Depression and Anxiety in Remitted Youth
5/1/202410 minutes, 22 seconds
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Charting the Clozapine Course: Titration and Monitoring

In this episode, we navigate the complexities of initiating and optimizing clozapine treatment for patients with treatment-resistant schizophrenia. How do you chart the course for successful clozapine therapy while managing side effects and drug interactions? Join us as Dr. Brian Miller shares his expertise and valuable psychopharmacology pearls. Faculty: Brian Miller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CMEs: Clozapine: Management and Challenges Initiating and Optimizing Clozapine
4/26/202415 minutes, 3 seconds
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Smoking and Psychosis: Insights from the PATH Study

In this episode, we discuss the prevalence of smoking among people with psychosis, based on recent findings from the PATH study. Dr. Oliver Freudenreich shares insights on how clinicians can prioritize smoking cessation in this population. How can we bridge the health outcome disparities faced by our patients with psychosis? Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 55 Tobacco Use, Nicotine Dependence, and Cessation Among Adults with Psychosis
4/21/202412 minutes, 17 seconds
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Clozapine: The Gold Standard for Treatment-Resistant Schizophrenia

In this episode, we delve into the use of clozapine for treatment-resistant psychosis and mood disorders. When should clinicians consider clozapine, and what do expert guidelines recommend? Dr. Brian Miller guides us through the evidence and best practices for utilizing this powerful but often underused medication. Faculty: Brian Miller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Clozapine: Management and Challenges Using Clozapine for Treatment-Resistant Psychosis and Mood Disorders
4/16/20249 minutes, 29 seconds
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Balancing Benefits and Risks: Lithium in Child and Adolescent Psychiatry

In this episode, we explore the role of lithium in treating pediatric bipolar disorder and conduct disorder. Is lithium a viable option for managing these complex conditions in children and adolescents, or are other medications more effective? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 14 Use of Lithium in Pediatric Bipolar Disorders and Externalizing Childhood-Related Disorders
4/11/202410 minutes, 55 seconds
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Orchestrating Nutrition and Medication: Micronutrient Therapy in Practice

In this episode, we explore real-world clinical cases demonstrating how broad-spectrum micronutrients can complement existing interventions for ADHD, emotional dysregulation, and mood instability. Can close monitoring and expert guidance optimize the integration of nutritional supplementation with pharmacologic treatments to create a harmonious, personalized approach? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Broad-Spectrum Micronutrients (BSMs) for Mental Health: What You Need to Know for Clinical Use Clinical Cases
4/6/20249 minutes, 14 seconds
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Zuranolone: A New Dawn for Postpartum Depression Treatment

In this episode, we discuss the groundbreaking FDA approval of zuranolone, the first oral medication specifically targeting postpartum depression. Could zuranolone's novel mechanism of action as an allopregnanolone agonist herald a new era of rapid-onset, targeted treatments for this debilitating condition affecting 1 in 8 new mothers? Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 54 Zuranolone for the Treatment of Postpartum Depression
4/1/202412 minutes, 13 seconds
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Micronutrients for Psychiatric Disorders: Optimizing Clinical Use

In this episode, we explore practical clinical tips for using broad-spectrum micronutrient supplements to treat mental health conditions. Can an individual's nutritional needs surpass population standards? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Broad-Spectrum Micronutrients (BSMs) for Mental Health: What You Need to Know for Clinical Use Practical Tips for Using BSMs in the Clinical Practice
3/27/20248 minutes
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Olanzapine in Pregnancy: Examining the Risks

In this episode, we examine whether first-trimester exposure to the antipsychotic olanzapine increases the risk of major fetal malformations. Does stopping medication abruptly also carry risks? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 14 Risk of Major Malformations Following First-Trimester Exposure to Olanzapine
3/22/202410 minutes, 38 seconds
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Understanding Safety Risks of Broad-Spectrum Micronutrients

In this episode, we delve into the safety considerations of using broad-spectrum micronutrient formulas in mental disorder treatment, mainly how these supplements can interact with other medications. Is it safe to use these formulas alongside anesthesia during surgery? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Broad-Spectrum Micronutrients (BSMs) for Mental Health: What You Need to Know for Clinical Use BSMs and Drug Interactions
3/17/20246 minutes, 25 seconds
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The Role of Inflammation in Delirium: Can NSAIDs Help?

In this episode, we explore the potential of NSAIDs in delirium prevention. However, NSAIDs come with risks, such as GI bleeding or kidney injury. Can NSAIDs really help prevent delirium, and if so, how? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 54 Use of NSAIDs for Delirium Risk Reduction
3/12/202412 minutes, 48 seconds
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Beyond Medication: Exploring Nutritional Psychiatry

In this episode, we explore the unconventional yet promising treatment modality of using broad-spectrum micronutrient formulas in mental health care. We discuss the research and clinical trials that have been undertaken to test combinations of vitamins and minerals, focusing on their safety and efficacy. What are the potential side effects of using broad-spectrum micronutrient formulas? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Broad-Spectrum Micronutrients (BSMs) for Mental Health: What You Need to Know for Clinical Use BSMs: Safety and Tolerability
3/7/202411 minutes, 11 seconds
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Age Impact on Antidepressant Outcomes

In this episode, we discuss an insightful study by Strawn et al. that utilized a mega-analysis approach, combining data on over 900 MDD patients across lifespan treatment trials to elucidate differences in antidepressant treatment outcomes based on patient age. Does antidepressant efficacy differ across developmental stages—children, adolescents, and adults? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 13 Age's Impact on Antidepressant Response
3/2/202412 minutes, 35 seconds
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Dealing With Delirium in Patients With Advanced Cancer

What are some common signs that suggest a cancer patient may be developing delirium? In this episode, we explore the complex issue of delirium in advanced cancer patients. We discuss important considerations regarding medication management, the importance of distinguishing terminal from reversible delirium, and the role of antipsychotics and benzodiazepines in treatment. Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Depression, Anxiety, and Delirium in Patients With Cancer Management of Delirium in Patients With Cancer
2/26/202411 minutes, 20 seconds
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Rechallenging Clozapine: A Look at Colony Stimulating Factors

In this episode, we discuss the treatment of agranulocytosis or neutropenia in patients on clozapine therapy, a rare yet serious scenario that clinicians may encounter. We delve into the possibility of rechallenging clozapine treatment after such an event and explore the use of colony-stimulating factors. What's the likelihood of agranulocytosis while prescribing clozapine long term? Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 53 The Impact of Colony-Stimulating Factor on Clozapine Rechallenge Outcomes
2/21/20249 minutes, 18 seconds
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Managing Anxiety in Patients With Cancer

In this episode, we delve into the management of anxiety in cancer patients, including the effective psychotherapeutic interventions and pharmacologic options for treating anxiety in this vulnerable group. The episode also touches on the importance of cultural sensitivity and patient education when managing anxiety in cancer patients. Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Depression, Anxiety, and Delirium in Patients With Cancer Treating Anxiety Disorders in Patients With Cancer
2/16/20248 minutes, 21 seconds
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Managing Antidepressant Side Effects in Youth

In this podcast episode, Dr. David Rosenberg explores practical strategies to asess and manage common antidepressant side effects in the pediatric population. Get useful takeaways regarding activation, insomnia, withdrawal symptoms, and more. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 13 Managing Adverse Effects of Antidepressants in Youth
2/11/202413 minutes, 16 seconds
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Depressed Patient With Cancer? Here’s How to Treat

In this podcast episode, Jaroslava Salman, M.D., discusses the treatment options for depressed patients with cancer. Stay a step ahead in your practice with practical tips on which psychotherapies are helpful, which antidepressants to use and for how long, what to be mindful of, and even insights into prescribing stimulants. Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Depression, Anxiety, and Delirium in Patients With Cancer Treating Depressive Disorders in Patients With Cancer
2/6/202415 minutes, 7 seconds
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Brexanolone: A Quick Fix for Postpartum Depression and Anxiety?

In this podcast episode, Dr. Vivien Burt delves into a study on brexanolone for women with postpartum depression, anxiety, and insomnia. Listen in and find out the effect and time frame of brexanolone on these symptoms. Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 53 Effect of Brexanolone on Postpartum Depressive Symptoms, Anxiety, and Insomnia
2/1/202413 minutes, 56 seconds
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The Nitty-Gritty on Treatment Optimization for Tic Disorders in Youth

In this podcast, Dr. David Rosenberg offers practical insights into treatment optimization for youth with tic disorders. Listen in and find out which treatment modality takes precedence, which factors need to be considered, how long to use medication, and more. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.5 CMEs: Tic Disorders in Children and Adolescents Treatment Optimization for Tic Disorders
1/27/202413 minutes, 22 seconds
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Untangling Dilemmas: Youth Cannabis-ADHD-Stimulant Med Misuse

In this podcast, Dr. David Rosenberg expertly addresses the questions on what to do when your adolescent patient has ADHD but uses cannabis. Should you prescribe stiimulants or not? And what if they just want stimulants for better test scores? What do you do? Listen in as Dr. Rosenberg offers useful takeaways to help you with these (all too common) dilemmas. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 12 Prescribing Stimulants for Youth With ADHD and Co-Occurring Cannabis Use
1/22/202411 minutes, 51 seconds
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Tic Disorders and Psychiatric Comorbidities in Youth: Treatment Cheat Sheet

In this podcast, Dr. David Rosenberg delves into tic disorders and psychiatric comorbidities in youth. This includes ADHD, OCD, anxiety and depression, and disruptive behaviors. Jump in and listen to practical treatment options for these cases, and stay one step ahead in your clinical practice. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.5 CME: Tic Disorders in Children and Adolescents Tic Disorders and Psychiatric Comorbidities
1/17/202412 minutes, 11 seconds
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Clinician’s Digest: CANMAT and Mixed States Practicalities

CANMAT presents a spectrum approach to mixed states. In this podcast, Dr. Jim Phelps delves into this and the DSM-5 approach, where mixed states became a specifier that can be added to a diagnosis of unipolar depression, effectively creating a spectrum approach to the diagnosis of mixed mood disorders. So, what’s a clinician to do treatment-wise? Should we or should we not use antidepressants when 4 specific symptoms are present? Find the answer to these and other questions in this podcast. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 52 Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) Recommendations for the Management of Patients With Bipolar Disorder With Mixed Presentations
1/12/20249 minutes, 57 seconds
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Mystery No More: Understanding Tic Disorders in Pediatric Psychiatry

In this podcast episode, Dr. David Rosenberg provides a much-needed understanding of tic disorders in children and adolescents. Listen in to learn what a typical course of this disorder could look like, why you may not need to substitute methylphenidate in these patients, what happens when patients supress tics, and much more. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.5 CME: Tic Disorders in Children and Adolescents Understanding Tic Disorders
1/7/202414 minutes, 24 seconds
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Metformin for Youth on SGAs: Ready for Prime Time?

In this podcast, Dr. David Rosenberg explores a review on metformin for youth on SGAs. Is it effective in mitigating weight gain in this population? And more importantly, should you prescribe it ASAP? Listen in as Dr. Rosenberg answers these questions and others. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 12 Metformin for Weight Gain in Youth on Atypical Antipsychotics
1/2/202410 minutes, 27 seconds
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Diagnosing Bipolar Disorder Within a Mood Spectrum? Here’s How

In this podcast, Dr. Jim Phelps discusses the issue of diagnosing bipolar disorder within the framework of a mood spectrum. How bipolar should a patient be before switching treatment strategies? Listen in for tips and practical takeaways to answer this question and guide decision making. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 52 “Cade’s Disease” and Beyond: Misdiagnosis, Antidepressant Use, and a Proposed Definition for Bipolar Spectrum Disorder
12/28/202310 minutes, 41 seconds
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Zolpidem Is to Blame: Sleepwalking and Sleep-Related Eating Disorder

In this podcast, Dr. Schenck discusses zolpidem-induced sleeping disorder and eating disorder. Listen and find out important tips and considerations, such as this being more common in females, alerting bed partners, being careful with zolpidem doses over 10 mg, and more. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Parasomnias Triggered by Sedative-Hypnotics: Sleepwalking and Sleep-Related Eating Disorder Zolpidem-Induced Sleepwalking and SRED
12/23/202311 minutes, 20 seconds
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Cariprazine: A Good Option for Pediatric Patients?

Cariprazine may be a good option for pediatric patients with schizophrenia and bipolar I disorder. Listen as Dr. Rosenberg summarizes study findings, which may broaden your options with children and adolescents. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 11 Safety and Tolerability of Cariprazine in Pediatric Patients
12/18/20238 minutes, 59 seconds
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Sleepwalking and Sleep Driving: Medication to Be Aware Of

This podcast explores medication associated with sleepwalking and sleep driving, as well as recommendations for clinicians when prescribing them to patients. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Parasomnias Triggered by Sedative-Hypnotics: Sleepwalking and Sleep-Related Eating Disorder Medication-Induced SRED, Sleepwalking, and Sleepdriving  
12/13/20237 minutes, 21 seconds
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Olanzapine/Samidorphan: Good for Psychosis With Less Weight Gain?

In this episode, we explore whether the olanzapine–samidorphan combination helps with psychosis while halting weight gain. We also look into the cost vs benefit of the combination as well as the metabolic side effects. Faculty: James Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 51 Comparative Efficacy, Safety, and Acceptability of Pimavanserin and Other Atypical Antipsychotics for Parkinson’s Disease Psychosis: Systematic Review and Network Meta-Analysis
12/8/20238 minutes, 15 seconds
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Melatonin's Impact on Suicidality and Accidents in Adolescents

Can melatonin reduce the risk of suicidality, bodily injuries, falls, and accidents in children and adolescents? In this episode, we explore a study that delves into this question. Discover how sleep disturbances impact young individuals' health, development, cognitive skills, emotional regulation, and behavior. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 11 Melatonin Use and the Risk of Self-Harm and Unintentional Injuries in Youth
12/3/202311 minutes
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Understanding Sleep-Related Eating Disorder (SRED)

Do you know what sleep-related eating disorder (SRED) is and how it intertwines sleep and eating pathologically? In this episode, we delve into an in-depth analysis of SRED, elucidating its diagnostic criteria, key characteristics of the diagnosis, and some intriguing aspects related to this disorder. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Parasomnias Triggered by Sedative-Hypnotics: Sleepwalking and Sleep Related Eating Disorder Diagnosing Sleep-Related Eating Disorder (SRED)
11/28/20237 minutes, 56 seconds
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Pimavanserin: A Solution for Psychosis in Parkinson's Disease?

This episode explores the controversial role of pimavanserin in treating psychosis in Parkinson's disease. How does it compare with quetiapine or clozapine? Sneak peek: All of these medications are effective, yet none distinctly surpasses the others. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 51 Comparative Efficacy, Safety, and Acceptability of Pimavanserin and Other Atypical Antipsychotics for Parkinson’s Disease Psychosis: Systematic Review and Network Meta-Analysis
11/23/20238 minutes, 48 seconds
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Current Approaches to Treating Pediatric Bipolar Disorder

Pediatric bipolar disorder treatment has evolved significantly since 2005, moving beyond lithium to several FDA-approved treatments. However, the challenges remain: How do we choose the first-line treatment? How can we mitigate and monitor side effects? In this episode, we discuss the latest practice treatment algorithms for pediatric bipolar disorder. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 10 Psychopharmacologic Treatment Algorithms for Bipolar Disorder in Youth
11/18/202312 minutes, 4 seconds
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Exploring Pharmacogenomic Testing in MDD

Can pharmacogenomic testing improve the selection and dosing of antidepressants in patients with MDD? In this episode, we explore the findings of the PRIME Care trial and discuss the clinical significance of these tests.  Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 49 Effect of Pharmacogenomic Testing for Drug–Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial
11/13/20239 minutes, 17 seconds
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Broad-Spectrum Micronutrients: A New Frontier in ADHD Treatment

In this episode, we discuss the role of broad-spectrum micronutrients (BSMs) in managing symptoms of ADHD. We examine the rationale behind opting for alternative therapies for this condition and dissect the outcomes of an RCT involving BSMs for ADHD. Could micronutrients provide a comprehensive strategy for treating ADHD, thereby enhancing overall mental wellness? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Broad-Spectrum Micronutrients (BSM) for Mental Health: Context for Considering Micronutrient Treatment An Overview of Standard Treatment vs CAM for ADHD
11/8/20237 minutes, 37 seconds
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Predicting Nonadherence in ADHD: A Focus on Side Effects

Are you aware that a staggering 80% of ADHD patients report at least 1 side effect from their medication? In this episode, we discuss an analysis that seeks to answer an essential question: Can we predict medication nonadherence in adolescents and young adults with ADHD based on specific side effects? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 10 Reported Side Effects Associated With Medication Nonadherence Among Youth With ADHD
11/3/20239 minutes, 58 seconds
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How Nutrient Metabolism Influences Mental Health

Did you know that your genes could affect how your brain processes vital nutrients? In this episode, we delve into fascinating research on micronutrient supplementation for mental disorders, such as ADHD. Discover how our genetic makeup might dictate our nutrient needs and how this can influence mental health outcomes. Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Broad-Spectrum Micronutrients (BSM) for Mental Health: Context for Considering Micronutrient Treatment Rationale for Micronutrient Supplementation in Mental Illness  
10/29/20239 minutes
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Antipsychotics and Substance Use: A Fresh Look at Old Drugs

Could antipsychotic switching impact substance use in schizophrenia? In this episode, Dr. Jim Phelps explores the impact of antipsychotics on patients with schizophrenia and substance use disorder. He includes insights from national cohorts and clinical cases and delves into the potential effects of changing from risperidone to clozapine. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 49 Associations Between Antipsychotic Use, Substance Use, and Relapse Risk in Patients with Schizophrenia: Real-World Evidence From 2 National Cohorts
10/24/202310 minutes, 3 seconds
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The Effect of the Mediterranean Diet on Depression

Dive into the fascinating world of nutrition's impact on mental health in our latest episode. We explore intriguing studies on the Mediterranean diet's potential to alleviate depressive symptoms. Can a shift in dietary habits truly improve mental health? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Broad-Spectrum Micronutrients (BSM) for Mental Health: Context for Considering Micronutrient Treatment Depression and Mediterranean-Style Diet
10/19/20238 minutes, 53 seconds
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Racial Disparities in Pharmacologic Restraints

In this episode, we explore a pressing problem in pediatric psychiatry: The disparities in the use of pharmacologic restraints. How can we address these biases in our healthcare system? What role do behavioral interventions play in reducing the need for these measures? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 09 Disparities in Pharmacologic Restraint Use in Pediatric Emergency Departments
10/14/202312 minutes, 4 seconds
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Managing Orthostasis in Patients on Clozapine

In this episode, we discuss the causes of clozapine-induced orthostasis. Although some patients may develop tolerance, it can limit titration and potentially obstruct patients from reaching the plasma level where they respond well to the medication. There are practical management strategies for orthostasis, including slow titration based on patient complaints and encouraging fluid intake, among others. Faculty: Jonathan Meyer, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Managing Some Unique Nonhematologic Adverse Effects of Clozapine Managing Clozapine-Related Orthostasis
10/9/20238 minutes, 37 seconds
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Lavender Extract for Anxiety

In this episode, we discuss the potential of lavender extract, Silexan, as an alternative treatment for anxiety and insomnia with Dr. Jim Phelps. Is it truly a promising solution free from dependency and withdrawal symptoms or just an effective placebo? Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 48 Effect of Anxiolytic Drug Silexan on Sleep – A Narrative Review
10/4/20238 minutes, 32 seconds
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Psychopharmacology Insights: Clozapine and Constipation

In this episode, we explore a common yet severe side effect of clozapine: Constipation. Why does this drug cause such drastic changes in colonic transit times, and how can we manage it effectively? Faculty: Jonathan Meyer, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Managing Some Unique Nonhematologic Adverse Effects of Clozapine Managing Clozapine-Related Constipation
9/29/202312 minutes, 25 seconds
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Understanding the Cardiovascular Impact of ADHD Medication

In this episode, we discuss a comprehensive study on the potential cardiovascular risks of ADHD medication. Although these medications pose minimal risk for those without preexisting conditions, there seems to be an elevated risk for those with preexisting cardiovascular diseases. Should we confidently prescribe these medications? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about Silver and Gold memberships here Earn 0.5 CMEs: CAP Smart Takes Vol. 09 Risk of Cardiovascular Diseases Associated With Medications Used in ADHD
9/24/20239 minutes, 19 seconds
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Sialorrhea: A Clozapine Side Effect

In this episode, we delve into the problem of sialorrhea or excessive salivation in patients on clozapine. Why does this occur, and how can it be managed? Join us as Dr. Jonathan Meyer shares his expertise on this unique side effect. Faculty: Jonathan Meyer, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Managing Some Unique Nonhematologic Adverse Effects of Clozapine Managing Clozapine-Related Sialorrhea
9/19/202310 minutes, 46 seconds
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Inflammation and Antidepressants: A New Treatment Frontier?

Can a simple lab test guide our choice of antidepressants? Explore the intriguing link between inflammation, measured by C-reactive protein (CRP) levels, and the effectiveness of certain antidepressants in this episode. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 48 C-Reactive Protein Could Predict the Efficacy of SSRIs in Clinical Practice: A Cohort Study of Large Samples in the Real World
9/14/202310 minutes, 32 seconds
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Ketamine Therapy: A New Hope for Adolescent Depression?

Could ketamine be the breakthrough we need in treating adolescent depression? Join us in this episode as we explore the potential of ketamine therapy and its rapid antidepressant effects. Also, learn how ketamine works, its safety profile, and why it's not quite ready for mainstream use in adolescents. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 08 Ketamine for Adolescent Depression
9/9/202310 minutes, 43 seconds
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Unraveling Nightmares: Exploring REM Sleep Behavior Disorder

In this episode, we dive into the puzzling case of a 67-year-old man experiencing violent moving nightmares. Is it rapid eye movement sleep behavior disorder, frequent and recurring nightmares, night terrors, PTSD, or another parasomnia? Tune in as we explore potential diagnoses with our expert Dr. Carlos Schenck. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Parasomnias Triggered by Antidepressant Medications: REM SleepBehavior Disorder and Restless Legs Syndrome A Clinical Case and Exclusive Videos On RBD and RLS
9/4/202310 minutes, 17 seconds
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Acute Agitation and Dexmedetomidine: A Novel Treatment Approach

In this episode, we delve into a new horizon in the management of acute agitation. We discuss dexmedetomidine, a drug that's been around since 1999, recently reformulated into a sublingual film and FDA approved for treating agitation associated with schizophrenia or bipolar I or II disorder. We explore the results from a recent randomized trial and its potential for transforming psychiatric care. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 47 Sublingual Dexmedetomidine for the Treatment of Acute Agitation in Adults With Schizophrenia or Schizoaffective Disorder: A Randomized Placebo-Controlled Trial
8/30/20238 minutes, 14 seconds
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The Prevalence and Risks of RBD

In this episode, we dive into rapid eye movement sleep behavior disorder (RBD). Did you know that RBD's prevalence is on par with schizophrenia in middle-aged and older adults? Tune in as we explore the prevalence, assessment, and management of RBD, a condition that is not only a sleep disorder but a potential harbinger of severe neurological conditions, like Parkinson's Disease and Dementia with Lewy Bodies. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Parasomnias Triggered by Antidepressant Medications: REM Sleep Behavior Disorder and Restless Legs Syndrome Prevalence, Assessment, and Management of RBD
8/25/202310 minutes, 28 seconds
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ADHD Medication and Their Role in Anxiety and Depression

In this episode, we dive deep into the effects of ADHD medication on anxiety and depressive symptoms in children and adolescents. Can these medications significantly exacerbate symptoms of anxiety or depression? Or do these symptoms arise more from the underlying condition of ADHD? We will delve into these critical questions and more through a thorough exploration of a comprehensive meta-analysis. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 08 Impact of ADHD Medications on Anxiety and Depression in Youth
8/20/20239 minutes, 48 seconds
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In the Realm of Sleep: RBD Diagnosis Explained

In this episode, we delve deep into the diagnostic mysteries of RBD, the need for video polysomnography, and the mechanisms leading to RBD. Whether you are a veteran or new to the field, this episode promises to deepen your understanding of RBD. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Parasomnias Triggered by Antidepressant Medications: REM Sleep Behavior Disorder and Restless Legs Syndrome Diagnosing REM Sleep Behavior Disorder
8/15/20238 minutes, 38 seconds
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NAC in Schizophrenia: Pie in the Sky or Groundbreaking Solution?

Are we missing a vital piece in the schizophrenia treatment puzzle? In this episode, we explore the intriguing and controversial role of N-acetylcysteine (NAC) in schizophrenia. We dive deep into the evidence, the theories, and the ongoing debates about this seemingly simple over-the-counter supplement. Could NAC be the key to unlocking better outcomes for those with schizophrenia, or is it just another dead end? Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 47 Antipsychotic Augmentation With N-Acetylcysteine for Patients With Schizophrenia
8/10/20238 minutes, 14 seconds
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Child Psychiatry: NAC and SAMe

How can N-acetyl cysteine (NAC) and S-adenosyl methionine (SAMe) be effectively integrated into child and adolescent psychiatric treatment? In this episode, we dive deep into the world of NAC and SAMe and explore their potential applications, dosage, side effects, and more. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Natural Medications in Child and Adolescent Psychiatry Administration of N-Acetylcysteine and S-Adenosylmethionine in Children and Adolescents
8/5/20237 minutes, 21 seconds
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Youth Psychotropic Prescription Trends: Pandemic Influence

How has the use of antipsychotics among children and adolescents been affected by the COVID-19 pandemic in the United States? In this episode, we delve into pandemic-induced trends in youth psychotropic prescriptions. Uncover how COVID-19 reshaped mental health services and psychopharmacology among young individuals. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 07 Psychotropic Prescriptions in Youth During COVID-19 Pandemic
7/31/20238 minutes, 17 seconds
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Nature's Remedies in Youth: St. John's Wort and Valerian

Can nature’s remedies hold the key to mental well-being in our youth? In this episode, we delve into the potential uses and limitations of St. John’s wort and valerian in child and adolescent psychiatry and, most importantly, their evidence in treating psychiatric disorders in this population. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Natural Medications in Child and Adolescent Psychiatry St. John’s Wort and Valerian: Potential Indications in Children and Adolescents
7/26/202313 minutes, 2 seconds
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Exploring Serotonergic Antidepressants for PMDD

Have you ever pondered the mystery behind the effectiveness of different SSRI dosing strategies for premenstrual dysphoric disorder (PMDD)? In this episode, we delve deep into the complex world of PMDD treatments, focusing on the intriguing comparison between intermittent luteal phase dosing and continuous dosing of serotonergic antidepressants. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 46 Intermittent Selective Serotonin Reuptake Inhibitors for Premenstrual Syndromes: A Systematic Review and Meta-Analysis of Randomized Trials
7/21/202310 minutes, 20 seconds
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Exploring Omega-3's Role in Child Psychiatry

Have you ever wondered how natural remedies like omega-3 fatty acids might influence child and adolescent psychiatry? In this episode, we delve into the intriguing world of omega-3 fatty acids and their potential role in treating various psychiatric disorders in children and adolescents, such as major depressive disorder, bipolar disorder, ADHD, and ASD. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Natural Medications in Child and Adolescent Psychiatry Use of Omega-3 Fatty Acids in Children and Adolescents
7/16/202314 minutes, 33 seconds
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ADHD Meds for Preschoolers: Lisdexamfetamine

 Have you ever wondered about the safety and effectiveness of ADHD medications in preschoolers? In this episode, we discuss a pioneering double-blind, fixed-dose study exploring the use of lisdexamfetamine in children aged 4–5 years. We delve into the nuances of this complex topic, from the increasing trend of psychotropic medication use in young children, to the unique characteristics that distinguish lisdexamfetamine from other amphetamine medications. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 07 Efficacy and Safety of Lisdexamfetamine in Preschool Children with ADHD
7/11/20238 minutes, 15 seconds
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Using Ginkgo Biloba in Children

In this episode, we delve into the intriguing world of ginkgo biloba and its potential role in treating ADHD in children and adolescents. Can this ancient herbal remedy offer a valuable alternative or adjunctive therapy? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Natural Medications in Child and Adolescent Psychiatry Use of Ginkgo Biloba in Children and Adolescents
7/6/20239 minutes, 30 seconds
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Examining COVID's Lasting Effects in Psychiatry

In this episode, we delve into the intriguing world of COVID-19's long-term effects in psychiatry. We explore a groundbreaking study that examines the duration of COVID-associated psychiatric disorders and variations in susceptibility by age. How long do these disorders persist, and are certain age groups more affected? Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 46 Neurologic and Psychiatric Risk Trajectories After SARS-CoV-2 Infection: An Analysis of 2-Year Retrospective Cohort Studies Including 1,284,437 Patients
7/1/20239 minutes, 12 seconds
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Beyond SSRIs: Antipsychotic Augmentation in OCD

In this episode, you'll discover the preferred second-generation antipsychotics for augmenting treatment for obsessive-compulsive disorder: Risperidone and aripiprazole. We discuss their effectiveness and important considerations when choosing between them. What factors should clinicians weigh when deciding on an augmentation strategy? Faculty: David Osser, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Algorithm for the Pharmacotherapy of Obsessive-Compulsive Disorder Node 4: SSRI Augmentation With SGA
6/26/202311 minutes
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Overcoming Barriers to Metabolic Monitoring in Youth Treated With SGAs

In this episode, we focus on the challenges faced in metabolic monitoring of youth receiving second-generation antipsychotics (SGAs), including the strategies to overcome these barriers and ensure the long-term health of young patients on SGAs. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 06 Barriers to Metabolic Monitoring of SGAs in Youth
6/21/202311 minutes, 15 seconds
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Exploring Outcomes and Strategies in OCD Treatment After the First Trial

In this episode, we delve into the potential outcomes after the first SSRI trial for OCD. With SSRIs being a first-line treatment, understanding response patterns is crucial. What course of action should be taken when patients exhibit significant symptom improvement, partial relief, or no response? Discover when to discontinue, switch, or augment treatment. Faculty: David Osser, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Algorithm for the Pharmacotherapy of Obsessive-Compulsive Disorder Node 2: Potential Outcomes After the First Trial
6/16/202311 minutes, 56 seconds
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Diving Into the APA Annual Meeting: Highlights and Insights!

In this episode, Dr. Richard Seeber and his special guests, Dr. Lorena Rodriguez and Dr. Paz Badia, discuss the topics covered in the APA Annual Meeting 2023, from technology in mental health practice to the use of cognitive–behavioral therapy for suicide prevention. Get ready to explore topics like ECT, ADHD, women's health, and much more. How can the integration of technology revolutionize mental health practice? Faculty: Paz Badia, M.D. and Lorena Rodríguez, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here
6/11/202316 minutes, 43 seconds
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Exploring the Intriguing World of Microdosing Psilocybin

In this episode, we delve into the fascinating world of microdosing psilocybin. A recent randomized trial examined the effects of microdosing using various outcome measures. Surprisingly, the acute effects were significantly more intense for the active dose but only when participants correctly identified their experimental condition. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 45 Microdosing With Psilocybin Mushrooms: A Double-Blind Placebo-Controlled Study
6/6/20239 minutes, 1 second
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SSRIs for OCD: A Closer Look at First-Line Treatment

What factors should clinicians consider when choosing an SSRI for treating patients with OCD? In this episode, we dive into the first-line treatment for OCD: SSRIs. Discover the most effective SSRIs for treating OCD, recommended doses, and potential adverse effects. Faculty: David Osser, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Algorithm for the Pharmacotherapy of Obsessive-Compulsive Disorder Node 2: First-Line Treatment: SSRIs
6/1/202311 minutes, 11 seconds
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Exploring Nonstimulant Treatments for ADHD

Are there any particular situations where nonstimulant medications may be especially effective for ADHD? In this episode, we discuss nonstimulant treatments for ADHD. Although stimulants are commonly used for ADHD, nonstimulant options like atomoxetine, viloxazine, clonidine, and guanfacine have been FDA approved and can be equally effective in certain populations. Listen in as we share clinical pearls on how to tailor treatments for each patient's unique needs. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about Silver and Gold memberships here Earn 0.5 CMEs: CAP Smart Takes Vol. 06 Nonstimulant Treatments for ADHD
5/27/202310 minutes, 16 seconds
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Complexities of OCD Treatment: Comorbidities and Other Considerations

In this episode, we share insights into the comorbidities and other considerations that can impact the treatment algorithm for OCD. From the risks of medication use in pregnant women, to the challenges of treating OCD in patients with comorbid bipolar disorder, this episode provides valuable clinical pearls for clinicians looking to improve their approach to treating OCD. Faculty: David Osser, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Algorithm for the Pharmacotherapy of Obsessive-Compulsive Disorder OCD Comorbidities and Other Circumstances: Variations in the Treatment Algorithm
5/22/202310 minutes, 17 seconds
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Lamotrigine and Lithium Combination Therapy for Rapid Cycling Bipolar Disorder

In this episode, we discuss rapid cycling bipolar disorder and its treatment, focusing on the use of the combination of lamotrigine and lithium. We also highlight the importance of checking thyroid status and tapering antidepressants in patients with rapid cycling. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 45 Lamotrigine and Lithium Combination for Treatment of Rapid Cycling Bipolar Disorder: Results From Meta-Analysis
5/17/20239 minutes, 24 seconds
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Melatonin and Secretin for Youth

In this episode, we discuss the potential use of melatonin as a safe and effective pharmacotherapy for sleep disturbances in children with ADHD and ASD. Did you know that up to 80% of children with ASD experience sleep disorders? Listen in to learn how melatonin can help improve sleep onset and duration in these patients. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Atypical Psychopharmacologic Strategies for Children and Adolescents Potential Indications of Melatonin and Secretin in Children and Adolescents  
5/12/202312 minutes, 17 seconds
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Tackling NSSI in Adolescents: Can Medications Help?

Which medications are safe and effective for treating nonsuicidal self-injury (NSSI) in children and adolescents? In this episode, we discuss the use of psychotropic medications in treating NSSI, which is becoming increasingly common in this population and can predict future suicide attempts. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 05 Psychotropic Drugs for Treating Nonsuicidal Self‑Injury in the Youth
5/7/20238 minutes, 17 seconds
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D-Cycloserine for Anxiety Disorders in Youth

This episode discusses D-cycloserine’s potential indications and administration in children and adolescents, including the evidence for anxiety disorders, OCD, ASD, and PTSD. It also mentions the dosage, administration, benefits, and side effects of D-cycloserine in youth. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Atypical Psychopharmacologic Strategies for Children and Adolescents D-Cycloserine: Potential Indications and Administration in Children and Adolescents
5/2/202314 minutes, 8 seconds
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Clinical Significance of Antidepressants for the Treatment of Acute Depression

Antidepressants are commonly used to treat depression, but how effective are they? In this episode, we discuss the concept of the minimal clinically important difference (MCID) and how it can be applied to assess antidepressant efficacy in treating depression. Specifically, knowing MCID estimates helps to shed light on recent controversies regarding antidepressant efficacy. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 44 Estimates of the Minimal Important Difference to Evaluate the Clinical Significance of Antidepressants in the Acute Treatment of Moderate-To-Severe Depression - Part 2
4/27/20237 minutes, 51 seconds
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Memantine: Potential Indications in Youth

What is the role of memantine in pediatric populations? This episode discusses memantine’s potential indications and administration in children and adolescents, an explanation of the theory of glutamatergic dysregulation, and the evidence of memantine for ASD, OCD, and mood disorders. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Atypical Psychopharmacologic Strategies for Children and Adolescents Memantine: Potential Indications in Children and Adolescents
4/22/202312 minutes, 30 seconds
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Low-Dose Olanzapine for Anorexia Nervosa

In this episode, we examine the tolerability, safety, and effectiveness of low-dose olanzapine in adolescents with anorexia nervosa (AN). Learn about the potential benefits and risks of using olanzapine in AN patients and the importance of a multidisciplinary approach in treating this challenging population. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 05 Low-Dose Olanzapine for Treating Adolescents With Anorexia Nervosa
4/17/20239 minutes, 50 seconds
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Naltrexone in Youth: Exploring Potential Applications and Cautions

In this episode, we discuss the potential uses and challenges of naltrexone in children and adolescents while addressing the limited and conflicting evidence. We also examine the dosage, side effects, and important considerations for using naltrexone in young populations. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Atypical Psychopharmacologic Strategies for Children and Adolescents Naltrexone: Potential Indications and Administration in Children and Adolescents
4/12/202313 minutes, 13 seconds
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Lamotrigine Titration: Slowing Down for Safer Treatment

Would a slower lamotrigine titration rate decrease the likelihood of developing the dreaded lamotrigine-associated rash? This episode discusses the possible advantages of slower lamotrigine titration rates, tips for managing benign rashes, and when to rechallenge lamotrigine. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 44 Impact of Selected Initial Titration Schedules on Safety and Long-Term Effectiveness of Lamotrigine for the Treatment of Mood Disorders
4/7/202310 minutes, 26 seconds
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Using Benzodiazepines in Geriatric Patients

In this episode, we dive into a topic that's especially relevant for those working with older adults: The use of benzodiazepines and sedative-hypnotics. We explore the unique considerations of prescribing these medications to geriatric patients and the importance of deprescribing them when possible. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Updates on Geriatric Psychopharmacology Considerations for Using Benzodiazepines and Benzodiazepine Receptor Agonists in the Geriatric Population
4/2/20236 minutes, 49 seconds
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Lithium Use in Pediatric Patients

In this episode, we delve into lithium's efficacy and potential long-term effects in younger patients and what clinicians should carefully monitor in this population. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 04 Long-Term Effects of Lithium Use on Children and Adolescents
3/28/202312 minutes, 23 seconds
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Using Mood Stabilizers in the Geriatric Population

Are mood stabilizers the right choice for elderly patients? This episode discusses key insights about using mood stabilizers in the geriatric population, including side effects and monitoring for lithium, valproic acid, lamotrigine, carbamazepine, and gabapentinoids. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Updates on Geriatric Psychopharmacology Considerations for Using Mood Stabilizers in the Geriatric Population
3/23/20238 minutes, 14 seconds
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Bright Light Therapy for Perinatal Depression

Do you have a patient suffering from postpartum depression? In this episode, we discuss a new study on light therapy as a potential treatment for postpartum depression, including the response rate, adverse effects, and effects on sleep quality. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 43 Efficacy of Bright Light Therapy in Perinatal Depression: A Randomized, Double-Blind, Placebo-Controlled Study
3/18/20238 minutes, 22 seconds
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Using SSRIs in the Geriatric Population

This episode discusses some strategies for starting antidepressants in the elderly, the important role of titrating doses, the efficacy of SSRIs, the side effects and drug–drug interactions of different medications, and clinical tips for using SSRIs and SNRIs in this population. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Updates on Geriatric Psychopharmacology Using SSRIs and SNRIs in the Geriatric Population
3/13/202318 minutes, 8 seconds
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Safety and Efficacy of Duloxetine in Youth With MDD

Is duloxetine a viable option for youth with MDD? In this episode, we discuss the need for additional medication options in youth with depression as well as an RCT of duloxetine to assess its efficacy and a label extension trial to evaluate its long-term safety. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 04 Efficacy and Safety of Duloxetine in Children and Adolescents With MDD in Japan
3/8/20238 minutes, 24 seconds
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Challenges in Prescribing Psychotropics to the Geriatric Population

What are the most common challenges when prescribing psychotropics to older adults? This episode discusses the challenges in prescribing psychotropics to the geriatric population, such as poor medication adherence and the risks of inappropriate prescribing. It also introduces a clinical case and emphasizes the importance of medication reconciliation. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Updates on Geriatric Psychopharmacology Challenges in Prescribing Psychotropics in the Geriatric Population and Mrs. M’s Case
3/3/20237 minutes, 30 seconds
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Antidepressants and Vertebral and Hip Risk Fractures

In this episode, we discuss an updated review of 11 studies that seek to evaluate the effect of antidepressants on the risk of hip and vertebral bone fractures. Although the overall effect size seems large, the absolute risk increase might be small. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 43 Antidepressants and Vertebral and Hip Risk Fracture: An Updated Systematic Review and Meta-Analysis
2/26/20237 minutes, 41 seconds
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Antidepressants and Mood Stabilizers for Managing Explosive Behavior

Are antidepressants effective for managing explosive behavior? In this episode, we discuss the efficacy of antidepressants and mood stabilizers for managing explosive behavior, including some proposed doses of lithium and divalproex sodium, and the indications for using antidepressants. Faculty: Carrie Vaudreuil, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Managing Explosive Behavior in Children and Adolescents Antidepressants and Mood Stabilizers for Managing Explosive Behavior
2/21/20236 minutes, 55 seconds
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Risk of Substance Use Disorders in Children Treated With Psychotropics

In this episode, we discuss a meta-analysis that included 6 million patients to assess whether pharmacotherapy increases the risk of substance use or misuse, specifically the risk of using stimulant medications in children with ADHD. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Smart Takes Vol. 03 Impact of Pharmacotherapy of Childhood-Onset Psychiatric Disorders on the Development of Substance Use Disorders
2/16/202311 minutes, 21 seconds
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FGAs and SGAs for Managing Explosive Behavior

In this episode, we discuss the SGAs with the most evidence for explosive behavior, their side effects, and monitoring recommendations. We also address the reasons for considering other SGAs and clarify which FGA has the most evidence for aggression. Faculty: Carrie Vaudreuil, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Managing Explosive Behavior in Children and Adolescents First- and Second-Generation Antipsychotics for Managing Explosive Behavior
2/11/20238 minutes, 55 seconds
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Use of Metformin to Prevent Clozapine-Induced Weight Gain

Should we start prescribing metformin to our patients on clozapine? In this episode, we discuss several articles on the efficacy of clozapine in preventing clozapine-induced weight gain, including some evidence on when metformin is more effective. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 42 Metformin for the Prevention of Clozapine-Induced Weight Gain: A Retrospective Naturalistic Cohort Study
2/6/20237 minutes, 39 seconds
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Managing Acute Aggression in Children and Adolescents

In this episode, we discuss the management of acute aggression in children and adolescents, including therapeutic support for explosive behavior, psychosocial crisis management techniques, and the medications used for acute aggression. Faculty: Carrie Vaudreuil, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Managing Explosive Behavior in Children and Adolescents Management of Acute Aggression in Children and Adolescents
2/1/202313 minutes, 11 seconds
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Early Antipsychotic Nonresponse as a Predictor of Nonresponse

In this episode, we discuss whether early nonresponse in adolescents with first-episode psychosis predicts longer-term nonresponse and nonremission. We also explain when it is most likely that symptom improvement occurs and some other considerations when there is nonresponse. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: CAP Smart Takes Vol. 03 Early Antipsychotic Nonresponse as a Predictor of Nonresponse in Adolescents With Psychosis
1/27/202312 minutes, 29 seconds
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Differential Diagnosis of Explosive Behavior

In this episode, we discuss the differential diagnosis of explosive behavior in children and adolescents, including the differences in these behaviors when they are associated with mood or anxiety disorders and disruptive behavior disorders. Faculty: Carrie Vaudreuil, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Managing Explosive Behavior in Children and Adolescents Management of Acute Aggression in Children and Adolescents
1/22/20239 minutes, 10 seconds
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Long-Term Follow-Up of Schizophrenia in Youth

In this episode, we discuss the long-term follow-up of psychosis and schizophrenia in children and adolescents, including predictors of poor long-term outcomes and the comorbidities associated with schizophrenia in adults. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.5 CME: Publication Title Long-Term Follow-Up of Psychosis and Schizophrenia in Children and Adolescents
1/17/20235 minutes, 53 seconds
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The Serotonin Theory of Depression

In this episode, we discuss a recent systematic umbrella review of the evidence behind the serotonin theory of depression and the controversy this review has generated. We explore the evidence presented regarding the interplay between serotonin and depression and present concrete steps to address several concerns generated by the review. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 42 The Serotonin Theory of Depression: A Systematic Umbrella Review of the Evidence
1/12/202310 minutes, 13 seconds
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SSRIs and Type 2 Diabetes in Children and Adolescents

Is there an association between SSRIs and type 2 diabetes in children and adolescents? In this episode, we discuss whether there is an association. We also explain whether there is an intraclass risk among different SSRIs. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Smart Take Vol. 02 SSRIs and Risk of Type 2 Diabetes in Children and Adolescents
1/7/20239 minutes, 50 seconds
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Tips for Treating Schizophrenia in Children and Adolescents

In this episode, we discuss additional clinical tips for treating schizophrenia in children and adolescents, including the considerations for selecting antipsychotics, recommendations for nonresponse, and when to use clozapine. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.5 CME: Psychosis and Schizophrenia in Children and Adolescents Additional Clinical Tips for Treating Schizophrenia In Children and Adolescents
1/2/20237 minutes, 29 seconds
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Physical Activity to Prevent Depression

In this episode, we review the current literature on the association between exercise and the risk for depression. Specifically, how much physical activity is associated with a lower risk for depression? We also discuss the World Health Organization recommendations for the ideal range of physical activity. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 41 Association Between Physical Activity and Risk of Depression: A Systematic Review and Meta-Analysis
12/28/202210 minutes, 31 seconds
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Use of Antipsychotics for Treating Psychosis in Children and Adolescents

In this episode, we discuss treatment options for managing psychosis and schizophrenia in children and adolescents, including the FDA-approved antipsychotics for this population. We also explain medication dosing guidelines and monitoring recommendations.  Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Psychosis and Schizophrenia in Children and Adolescents Treatment of Psychosis and Schizophrenia in Children and Adolescents: Antipsychotic Dosing, Monitoring, and Side Effects
12/23/202219 minutes, 38 seconds
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Depression in Adolescents

Are antidepressants in adolescent depression associated with an increased risk for suicidality? In this episode, we discuss the particularities of adolescent depression, including some statistics and the risk of suicide when using antidepressants in this population. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Smart Take Vol. 02 Depression in Adolescents
12/18/202214 minutes, 4 seconds
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Diagnostic Evaluation of Psychotic Symptoms in Children and Adolescents

In this episode, we discuss the diagnosis of psychotic symptoms in children and adolescents, including the differences between primary and secondary psychosis and the rating scales for assessing these symptoms.  Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Psychosis and Schizophrenia in Children and Adolescents Diagnostic Evaluation of Psychotic Symptoms in Children and Adolescents
12/13/202215 minutes, 21 seconds
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Use of Folate and Its Derivatives in Depression

Can L-methylfolate help in depression treatment? Should we indicate it to all patients with depression? In this episode, we discuss the metabolic pathways for folic acid, when to indicate L-methylfolate, and when to perform genetic testing for methyltetrahydrofolate reductase (MTFR) enzymes.  Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 41 The Potential Use of Folate and Its Derivatives in Treating Psychiatric Disorders: A Systematic Review
12/8/202210 minutes, 4 seconds
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Antipsychotics and Cholinesterase Inhibitors for BPSD

Antipsychotics or cholinesterase inhibitors for BPSD? This episode discusses the evidence of antipsychotics and cholinesterase inhibitors for BPSD, including the risks of using antipsychotics in elderly patients. We also provide recommendations for treating patients with Parkinson’s disease and Lewy body dementia. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Management of Behavioral and Psychological Symptoms of Dementia Antipsychotics and Cholinesterase Inhibitors for BPSD
12/3/20229 minutes, 19 seconds
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SGAs in Youth With Bipolar Depression

What are the safest and most effective medications for depression in youth with bipolar disorder? In this episode, we compare the response rates of quetiapine, olanzapine, and lurasidone for bipolar depression in youth. This episode also explains the differences in metabolic side effects and discusses the limitations of this study.  Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Smart Take Vol. 01 Efficacy and Safety of SGAs in Youth With Bipolar Depression
11/28/202211 minutes, 57 seconds
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Pharmacologic Treatments for BPSD

This episode discusses the pharmacologic treatments for BPSD, including the indications for using psychotropic medications as first-line treatment. It also explains when medications are ineffective and when to use them as a temporary measure. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Management of Behavioral and Psychological Symptoms of Dementia Overview of Pharmacologic Treatment for BPSD
11/23/20227 minutes, 47 seconds
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Association Between FIASMA Psychotropics and COVID-19

What are FIASMA psychotropics? What do they have to do with COVID-19? In this episode, we discuss a recent study that compared rates of severe illness among patients who, when admitted for COVID-19, were or were not taking a FIASMA—a functional inhibitor of acid sphingomyelinase activity. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 40 Association Between FIASMA Psychotropic Medications and Reduced Risk of Intubation or Death in Individuals With Psychiatric Disorders Hospitalized for Severe COVID-19: An Observational Multicenter Study
11/18/202210 minutes, 42 seconds
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Treatment Approaches for BPSD

Are antipsychotics the answer to the chaos of dementia? In this episode, we discuss the pharmacologic and nonpharmacologic treatment approaches to address BPSD, including the risks of using antipsychotics and the causes of death related to their use.  Faculty: Lauren Gerlach, D.O.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Management of Behavioral and Psychological Symptoms of Dementia Pharmacologic and Nonpharmacologic Treatment Approaches
11/13/20228 minutes, 24 seconds
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Brexpiprazole for Borderline Personality Disorder

In this episode, we discuss a recent RCT on using brexpiprazole to treat borderline personality disorder. Is it safe and effective? Could brexpiprazole be the magic bullet we were waiting for?  Faculty: Jim Phelps, M.D.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 40 A Double-Blind Placebo-Controlled Study of Brexpiprazole for the Treatment of Borderline Personality Disorder
11/8/20228 minutes, 6 seconds
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Patient, Caregiver, and Environmental Factors Underlying BPSD

This episode discusses the patient factors underlying BPSD, such as neurodegeneration, acute medical issues, medication changes, pain, and psychiatric diagnoses. It also explains caregiver and environmental factors and the concept of the “broken brain.”  Faculty: Lauren Gerlach, D.O.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Management of Behavioral and Psychological Symptoms of Dementia Understanding Patient, Caregiver, and Enviromental Factors
11/3/202211 minutes, 29 seconds
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Long-Term Treatment With Methylphenidate in Preschool Children

Is it safe to use stimulants in preschool children with ADHD? In this episode, we discuss the long-term symptom control and safety of an ER methylphenidate compound in preschool children 4 to Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Smart Take Vol. 1 Long-Term Treatment With Extended-Release Methylphenidate Treatment in Younger Children
10/29/20229 minutes, 59 seconds
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Use of Psychotropics in Patients With Hepatic Issues

How to determine whether hepatic impairment can affect drug metabolism? This episode discusses practical considerations when prescribing psychotropic medications for patients with hepatic issues. It also clarifies dosing considerations for specific medications, such as clozapine and valproate, in the context of patients with hepatic issues.  Guest: Jonathan Meyer, M.D.  Interviewer: Mohan Gautam, M.D.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Use of Psychotropics in Patients With Hepatic Issues - Interview with Jonathan M. Meyer, M.D.
10/24/202218 minutes, 37 seconds
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Important Considerations for Switching to Clozapine

How to titrate clozapine in inpatients and outpatients? In this episode, we discuss important considerations for switching to clozapine, including the indications and clinical scenarios for using it. This episode also explains precautions while titrating clozapine and how to reduce the preswitch antipsychotic.  Faculty: Brian Miller, M.D.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Antipsychotic Switching: Intersection of Art and Science Important Considerations for Switching to Clozapine
10/19/202215 minutes, 3 seconds
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Pharmacologic and Psychosocial Interventions for Reducing Irritability in Youth With ADHD

In this episode, we discuss the interventions found to be efficacious in youth with ADHD. Specifically, would treatment with stimulants be effective at reducing irritability in youth with ADHD?  Faculty: Jim Phelps, M.D.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 39 A Mini-Review of Pharmacologic and Psychosocial Interventions for Reducing Irritability Among Youth With ADHD
10/14/20229 minutes, 2 seconds
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Switching From Oral Antipsychotics to LAIs

This episode discusses antipsychotic switching from oral antipsychotics to LAIs, including the factors to consider when titrating antipsychotics and establishing PO tolerability before switching to an LAI.  Faculty: Brian Miller, M.D.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Antipsychotic Switching: Intersection of Art and Science Types of Antipsychotic Switching: Between PO Agents and From PO to LAI
10/9/202212 minutes, 22 seconds
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Medications for Rapid Tranquilization of Agitated Patients

In this episode, we discuss a systematic review and network analysis that compares 11 medications for treating severe agitation in the emergency department. Which medications have been shown to work best?  Faculty: Jim Phelps, M.D.  Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 39 Rapid Tranquilization of the Agitated Patient in the Emergency Department: A Systematic Review and Network Meta-Analysis
10/4/20228 minutes, 37 seconds
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Strategies for Antipsychotic Switching

Which is the preferred strategy for switching from one antipsychotic to another? This episode discusses strategies for antipsychotic switching: Abrupt, cross-taper, taper, and plateau cross-taper switch.                               Faculty: Brian Miller, M.D. Hosts: Jessica Diaz, M.D., Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Antipsychotic Switching: Intersection of Art and Science Strategies for Antipsychotic Switching  
9/29/20229 minutes, 54 seconds
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The Psychopharmacology of Eating Disorders

Are there FDA-approved medications for eating disorders? In this episode, we discuss management strategies for eating disorders, including the use of FDA-approved medications, the importance of cognitive–behavioral interventions, and the need to reduce stigma in these disorders.  Guest: Timothy Brewerton, M.D.  Interviewer: Wegdan Rashad, M.D.  Hosts: Jessica Diaz, M.D.; Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: The Psychopharmacology of Feeding and Eating Disorders - Interview with Timothy Brewerton, M.D.,DLFAPA, FAED, DFAACAP, CEDS-S
9/24/202220 minutes, 13 seconds
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Relative Contraindications to Antipsychotic Switching

What are the contraindications to antipsychotic switching? This episode discusses the relative contraindications of antipsychotic switching, including recent recovery from an acute psychotic episode, current stability on an LAI, and history of violence or severe symptoms.  Faculty: Brian Miller, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: Antipsychotic Switching: Intersection of Art and Science Relative Contraindications to Antipsychotic Switching
9/19/20228 minutes, 7 seconds
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Reasons for Stopping Clozapine

Why do patients stop clozapine?  This episode discusses clozapine discontinuation rates and reasons for doing so among patients who later recommenced clozapine therapy.  Faculty: Jim Phelps, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 38 Demographic and Clinical Characteristics of Patients Who Recommence Clozapine Following Therapy Interruptions
9/14/20228 minutes, 36 seconds
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Assessing and Treating an Adolescent With OCD

Sharpen your clinical skills with a clinical case of an adolescent girl with OCD. This episode also reviews the progression and consequences of the patient’s symptoms, the diagnosis, and the best treatment options for improving her symptoms.  Faculty: David Rosenberg, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: OCD in Children and Adolescents Assessing and Treating Jane
9/9/20227 minutes, 46 seconds
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Mirtazapine for Agitated Behaviors in Dementia

In this episode, Dr. Phelps discusses a study on the efficacy and safety of mirtazapine for treating agitation in patients with dementia. Would prescribing mirtazapine be worth the risk?  Faculty: Jim Phelps, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 38 Study of Mirtazapine for Agitated Behaviors in Dementia (SYMBAD): A Randomised, Double-Blind, Placebo-Controlled Trial    
9/4/202210 minutes, 6 seconds
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Clinical Tips for Treating Treatment-Resistant OCD in Youth

Can we use clomipramine in children? This episode discusses tips for clinicians treating pediatric OCD, follow-up on pediatric OCD symptoms into adulthood, and treatment response in OCD. It also reviews the use of clomipramine for treatment-resistant OCD and its requirements and precautions. Faculty: David Rosenberg, M.D. Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: OCD in Children and Adolescents Clinical Tips for Treating Pediatric OCD, Long-Term Follow-Up, and Treatment-Resistant OCD
8/30/20227 minutes, 46 seconds
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GAD Psychopharmacology Algorithm

How should we treat patients with bipolar disorder and comorbid GAD? In this episode, Dr. David Osser discusses an evidence-based treatment algorithm for the treatment of generalized anxiety disorder. He also clarifies common clinical concerns, such as treating GAD in patients with comorbid conditions and treatment resistance.  Guest: David Osser, M.D.  Interviewer: Mohan Gautam, D.O.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: GAD Psychopharmacology Algorithm -Interview with David Osser, M.D. Psychopharmacology Algorithms from Psychopharmacology Algorithms Project at the Harvard South Shore Psychiatry Residency Training Program
8/25/202219 minutes
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Guidelines for Managing Pediatric OCD

What are the FDA-approved medications for pediatric OCD? This episode discusses the guidelines for the management of pediatric OCD, including the treatment for mild, moderate, and severe OCD symptoms, as well as the recommended treatment for remission and maintenance, partial response, and nonresponse. It also examines medication dosing guidelines and FDA-approved medications.  Faculty: David Rosenberg, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: OCD in Children and Adolescents Guidelines for the Management of Pediatric OCD
8/20/202217 minutes, 34 seconds
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Ketamine Plus Psychotherapy for AUD

Can ketamine be an effective adjunctive treatment to sustain abstinence from alcohol? In this episode, Dr. Phelps discusses a double-blind, placebo-controlled trial of adjunctive ketamine with mindfulness psychotherapy for treating alcohol use disorder.  Faculty: Jim Phelps, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 37 Adjunctive Ketamine With Relapse Prevention-Based Psychological Therapy in the Treatment of Alcohol Use Disorder
8/15/202210 minutes, 47 seconds
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Pediatric OCD Comorbid With GAD, MDD, and ASD

How to untangle pediatric OCD from ASD and GAD? This episode discusses pediatric OCD and its comorbidities: Depression, GAD, and ASD. It includes a discussion on the differences in concerns between OCD and GAD, the assessment of primary and secondary depressive symptoms, and the differences between ASD and OCD rituals.  Faculty: David Rosenberg, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: OCD in Children and Adolescents Pediatric OCD Comorbidity With Depression, Anxiety Disorders, and ASD
8/10/202211 minutes, 35 seconds
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rTMS for Smoking Cessation

Have you ever imagined using rTMS for patients who struggle to quit smoking? This episode discusses a double-blind RCT that assessed the efficacy of rTMS in patients with tobacco use disorder who had at least 1 prior failed attempt to quit. Faculty: Jim Phelps, M.D. Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 37 Repetitive Transcranial Magnetic Stimulation for Smoking Cessation: A Pivotal Multicenter Double‐Blind Randomized Controlled Trial
8/5/202210 minutes, 8 seconds
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Good Psychiatric Management for BPD

Learn some of the recommendations from the Handbook of Good Psychiatric Management for Borderline Personality Disorder.  This episode addresses the clinical approach and drug management in the good psychiatric management of BPD.  Faculty: Paul Links, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Pharmacologic Management of BPD: Recent Developments Good Psychiatric Management for BPD  
7/31/20228 minutes, 2 seconds
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Tips for Diagnosing and Treating OCRDs

How do you distinguish obsessive-compulsive and related disorders from habits? In this episode, we discuss the varying presentations of OCRDs and challenges in their management, including practical recommendations for psychopharmacologic management.  Guest: Robert Hudak, M.D.  Interviewer: Wegdan Rashad, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Obsessive-Compulsive and Related Disorders - Interview with Robert Hudak, M.D.
7/26/202220 minutes, 16 seconds
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Medications Under Investigation for BPD

What other medications can we offer to our patients with BPD? This episode discusses some novel medication approaches used in borderline personality disorder, including omega-3 fatty acids, methylphenidate, clonidine, doxazosin, memantine, and oxytocin.  Faculty: Paul Links, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Pharmacologic Management of BPD: Recent Developments Omega-3 Fatty Acids, Methylphenidate, Clonidine, Doxazosin, Memantine, and Oxytocin for BPD
7/21/20229 minutes, 56 seconds
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Lithium Efficacy for Preventing Suicide

Is lithium really effective in patients with a high risk of suicide? In this episode, Dr. Phelps discusses a randomized clinical trial that assessed the efficacy of adding lithium to an existing medication regimen for reducing the rate of suicide-related events in veterans with bipolar disorder and depression.  Faculty: Jim Phelps, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 36 Lithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder
7/16/202210 minutes, 49 seconds
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Mood Stabilizers for BPD

Are mood stabilizers effective for borderline personality disorder? This episode discusses the use of lamotrigine and lithium in BPD patients, including possible benefits, concerns, and recommendations regarding these medications.  Faculty: Paul Links, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Pharmacologic Management of BPD: Recent Developments Mood Stabilizers for BPD: Lamotrigine and Lithium
7/11/20228 minutes, 28 seconds
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Anxiety and Sleep Problems in Children and Adolescents

Should we target anxiety disorders and sleep-related problems simultaneously? In this episode, Dr. Phelps discusses a narrative review to provide an overview of the evidence of the associations between anxiety disorders and sleep-related problems in children and adolescents.  Faculty: Jim Phelps, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 36 Treatment Implications of Sleep‑Related Problems in Pediatric Anxiety Disorders: A Narrative Review of the Literature
7/6/202211 minutes, 8 seconds
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Antipsychotics for Borderline Personality Disorder

This episode discusses the use of antipsychotics in patients with borderline personality disorder, including specific information on quetiapine and clozapine and some tips regarding the use of antipsychotics in these cases.               Faculty: Paul Links, M.D. Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Pharmacologic Management of BPD: Recent Developments Antipsychotics for BPD
7/1/20227 minutes, 5 seconds
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Treating Alcohol Use Disorder

Which medications can we offer for alcohol use disorder? This episode will offer practical tips for selecting and initiating medications for managing patients with at-risk drinking and alcohol use disorder. Guest: Joji Suzuki, M.D. Interviewer: Wegdan Rashad, M.D. Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: What Clinicians Need to KnowAbout Alcohol Use Disorder -Interview with Joji Suzuki, M.D.  
6/26/202218 minutes, 49 seconds
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Topiramate and Stimulant Replacement Therapy for Cocaine Use Disorder

This episode discusses the evidence and benefits of topiramate and stimulant replacement therapy for cocaine use disorder. It also addresses the use of these medications when there are comorbidities, such as alcohol use disorder and ADHD.  Faculty: Andrew Saxon, M.D.  Hosts: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: Experimental Pharmacotherapies for Stimulant Use Disorder Topiramate and Methylphenidate for Cocaine Use Disorder and Its Comorbidities
6/21/202212 minutes, 21 seconds
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Association Between Mood Disorders and COVID-19

In this episode, we discuss the problem of pre-existing mood disorders increasing the risk of hospitalization and death among people infected with COVID-19. Why does this occur? Faculty: Jim Phelps, M.D. Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 34 Association Between Mood Disorders and Risk of COVID-19 Infection, Hospitalization, and Death  
6/16/20229 minutes, 7 seconds
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Antidepressants and Naltrexone for Stimulant Use Disorder

This episode discusses the evidence of mirtazapine, bupropion, and naltrexone for stimulant use disorder. Are these promising treatments? Are they really effective?  Faculty: Andrew Saxon, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: Experimental Pharmacotherapies for Stimulant Use Disorder Antidepressants and Naltrexone for Methamphetamine Use Disorder
6/11/202211 minutes, 7 seconds
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CANMAT Task Force Recommendations for the Use of Ketamine

Can we use ketamine as a maintenance treatment for MDD? In this episode, Dr. Phelps discusses CANMAT’s recommendations for the use of ketamine for MDD. Faculty: Jim Phelps, M.D. Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 35 The Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Recommendations for the Use of Racemic Ketamine in Adults With Major Depressive Disorder
6/6/202210 minutes, 37 seconds
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Stimulant Replacement Therapies for Methamphetamine and Amphetamine Use Disorder

Can methylphenidate help amphetamine and methamphetamine use disorder? This episode discusses stimulant replacement therapies for methamphetamine and amphetamine use disorder. This includes the possible use of MPH in patients with underlying ADHD.  Faculty: Andrew Saxon, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: Experimental Pharmacotherapies for Stimulant Use Disorder Stimulant Replacement Therapies for Methamphetamine and Amphetamine Use Disorder
6/1/202210 minutes, 13 seconds
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Premenstrual Mood Syndromes

What is the first-line treatment for premenstrual mood syndromes? In this episode, Dr. Lauren Osborne discusses premenstrual mood syndromes and offers valuable insights regarding their management. She also discusses novel medications, such as brexanolone and drospirenone.  Guest: Lauren Osborne, M.D.  Interviewer: Wegdan Rashad, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Premenstrual Mood Syndromes -Interview with Lauren Osborne, M.D.
5/27/202219 minutes, 4 seconds
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Stimulant Use Disorder: Diagnosis and Assessment

This episode discusses the course and prognosis for stimulant use disorder as well as how to diagnose and assess this disorder. It also explains the loss of control over stimulant use, dysfunctional behaviors, co-occurring psychiatric disorders, and medical side effects.  Faculty: Andrew Saxon, M.D. Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 1 CME: Experimental Pharmacotherapies for Stimulant Use Disorder Stimulants Use: Course, Assessment, and Diagnosis
5/22/202210 minutes, 28 seconds
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Zuranolone for Postpartum Depression

Should zuranolone be a first-line treatment for postpartum depression? In this episode, Dr. Phelps discusses a randomized trial of zuranolone—a new neuromodulatory steroid—in the context of previous guidelines for the treatment of postpartum depression.  Faculty: Jim Phelps, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 35 Effect of Zuranolone vs Placebo in Postpartum Depression  
5/17/20229 minutes, 23 seconds
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Long-Term Treatment of First Episode of Psychosis

How long should we continue antipsychotic treatment in FEP? This episode discusses the long-term treatment of FEP, including the duration of antipsychotic treatment and the effects of dose reduction, the pros and cons of antipsychotic treatment, and the importance of collaborative treatment.  Faculty: Stephen Marder, M.D.  Host: Jessica Diaz, M.D. Learn more about our memberships here Earn 0.75 CMEs: Assessment and Management of First Episode of Psychosis Long-Term Treatment of FEP
5/12/20228 minutes, 54 seconds
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The Effects of Antipsychotic Treatment on the Brain of Patients With First-Episode Schizophrenia

In this episode, Dr. Phelps discusses the recent literature on brain volume changes after first-episode psychosis. What causes brain volume reductions—the illness or antipsychotics?  Faculty: Jim Phelps, M.D.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 34 The Effects of Antipsychotic Treatment on the Brain of Patients With First-Episode Schizophrenia: A Selective Review of Longitudinal MRI Studies    
5/7/20229 minutes, 11 seconds
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Health Issues in First Episode of Psychosis

Do people with schizophrenia already have a high risk of metabolic effects early in the course of illness? This episode discusses health concerns for first-episode patients, including life expectancy, metabolic conditions in drug-naïve patients, the signs of developing insulin resistance, and the approaches for early metabolic changes.  Faculty: Stephen Marder, M.D.  Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 0.75 CMEs: Assessment and Management of First Episode of Psychosis Health Concerns for First-Episode Patients  
5/2/20229 minutes, 43 seconds
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Psychopharmacology for Treatment-Resistant Early Psychosis

This episode discusses treatment-resistant early psychosis, including treatment with LAIs and the use of clozapine for treatment-resistant cases.  Faculty: Stephen Marder, M.D.  Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 0.75 CMEs: Assessment and Management of First Episode of Psychosis Psychopharmacology for People With Treatment-Resistant Early Psychosis
4/27/20228 minutes, 34 seconds
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Assessing and Treating Adult ADHD

Does adult-onset ADHD really exist? This episode discusses the neurobiological underpinnings of adult ADHD. It also describes how to assess adults with ADHD, important considerations, and some management strategies.  Guest: Oscar Bukstein, M.D.  Interviewer: Mohan Gautam, D.O.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: The Clinical Guide to Adult ADHD -Interview with Oscar Bukstein, M.D., M.P.H.
4/22/202219 minutes, 26 seconds
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Medications for Binge Eating Disorder

Is binge eating an addictive disorder or an impulse-control disorder? In this episode, Dr. Phelps summarizes the evidence of efficacy of several medications for binge eating disorder. He also discusses the psychopathology and neuropharmacology of binge eating disorder.  Faculty: Jim Phelps, M.D.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 33 Prospects for New Drugs To Treat Binge Eating Disorder: Insights From Psychopathology and Neuropharmacology
4/17/202212 minutes, 2 seconds
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Antipsychotics for First Episodes of Psychosis

This episode discusses considerations when treating first-episode psychosis with antipsychotics, treatment principles and response, and early predictors of poor long-term course.  Faculty: Stephen Marder, M.D.  Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 0.75 CMEs: Assessment and Management of First Episode of Psychosis Management of First Episodes: Antipsychotics
4/12/20229 minutes, 3 seconds
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Effects on Suicidal Risk With Different Medications

This episode discusses whether clozapine and other medications can reduce the risk of suicide. Is it a "class effect" of antipsychotics, or is it specific to clozapine?  Faculty: Jim Phelps, M.D.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 33 Effects on Suicidal Risk: Comparison of Clozapine to Other Newer Medicines Indicated to Treat Schizophrenia or Bipolar Disorder
4/7/20229 minutes, 37 seconds
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Risks of Using Cannabinoids

What are the risks associated with cannabinoid use? This episode discusses some risks, such as overdose, increased ER visits, and cardiovascular risks as well as the effects on pulmonary health.  Faculty: Diana Martinez, M.D.  Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 0.75 CMEs: Medicinal Cannabis and the Psychiatric Patient: Clinical Harm vs Novel Treatment Cannabinoids and Risks for Patients  
4/2/202210 minutes, 22 seconds
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Lithium: How to Manage Dosage

How do you titrate lithium doses? In this episode, Dr. David Osser discusses practical insights on lithium dosing and monitoring strategies.  Guest: David Osser, M.D.  Interviewer: Mohan Gautam, D.O.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Lithium: How to Manage Dosage andSide Effects and Persuade Patients toTake It - Interview with David Osser, M.D.  
3/28/202219 minutes, 37 seconds
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CBD as a Medication

Can we use CBD for psychiatric disorders? This episode discusses the evidence for medical uses of CBD for various disorders, such as childhood epilepsy, schizophrenia, social anxiety disorder, opioid use disorder, and cannabis use disorder.                                               Faculty: Diana Martinez, M.D. Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 0.75 CMEs: Medicinal Cannabis and the Psychiatric Patient: Clinical Harm vs Novel Treatment Understanding the Evidence for CBD  
3/23/20227 minutes, 58 seconds
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SSRIs and Suicidality

Do SSRIs really increase suicide risk? This episode discusses the controversial literature regarding the effect of antidepressant initiation on suicidal ideation.  Faculty: Jim Phelps, M.D.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 32 Suicidality and Self-Injury With Selective Serotonin Reuptake Inhibitors in Youth: Occurrence, Predictors, and Timing
3/18/20229 minutes, 41 seconds
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Cannabis and Cognition

Does cannabis use cause cognitive deficits? This episode discusses cannabis use and its long-term effects on cognition in adults and younger people.  Faculty: Diana Martinez, M.D. Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 0.75 CMEs: Medicinal Cannabis and the Psychiatric Patient: Clinical Harm vs Novel Treatment Cannabis and Cognition
3/13/20227 minutes, 33 seconds
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Clozapine-Induced Myocarditis

When should you suspect clozapine-induced myocarditis? Myocarditis has nonspecific manifestations. In this episode, Dr. Phelps explains the clinical presentation and the steps to take if you suspect myocarditis. Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 32 Clozapine-Induced Myocarditis: Electronic Health Register Analysis of Incidence, Timing, Clinical Markers, and Diagnostic Accuracy  
3/8/20229 minutes, 46 seconds
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Does Cannabis Use Cause Psychiatric Disorders?

This episode discusses cannabis use in patients with a psychiatric disorder. It also addresses the risk of psychosis in people who use cannabis and the relationship to schizophrenia.  Faculty: Diana Martinez, M.D.  Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 0.75 CMEs: Medicinal Cannabis and the Psychiatric Patient: Clinical Harm vs Novel Treatment Does Cannabis Use Cause Psychiatric Disorders?
3/3/20229 minutes, 35 seconds
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Treatment Strategies for Treatment-Resistant OCD

When a patient does not respond to an SSRI trial, what is the best strategy—increase the dose, augment with another agent, or switch to another SSRI? In this interview, Dr. Hudak discusses dosing strategies and the treatment of patients with OCD and comorbid psychiatric conditions.  Guest: Robert Hudak, M.D.  Interviewer: Mohan Gautam, D.O.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Treatment-Resistant Obsessive-Compulsive Disorder - Interview with Robert Hudak, M.D.
2/26/202219 minutes, 30 seconds
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Lithium Augmentation for Psychotic Depression

This episode discusses lithium augmentation for psychotic depression, including evidence from different case series and open-label studies. It also addresses some clinical strategies for lithium augmentation.  Faculty: David Osser, M.D.  Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 1.25 CMEs: The Psychopharmacology Algorithm for Psychotic Depression Node 5: Lithium Augmentation  
2/21/20228 minutes, 56 seconds
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Prevention and Treatment Strategies for Agitation and Dementia

Which medications can be used for acute and chronic agitation in dementia? For acute agitation, you might consider the use of haloperidol. For chronic agitation, you could consider citalopram: Its efficacy has been found to be equal to that of antipsychotics in randomized trials. Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 31 Agitation and Dementia: Prevention and Treatment Strategies in Acute and Chronic Conditions
2/16/202210 minutes, 18 seconds
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Choosing an Antipsychotic for Psychotic Depression

This episode discusses how to choose an antipsychotic for psychotic depression combination therapy. It also reviews the efficacy and side effects of first- and second-generation antipsychotics and the evidence of SGAs for psychotic depression.  Faculty: David Osser, M.D.  Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 1.25 CMEs: The Psychopharmacology Algorithm for Psychotic Depression Node 2: Choosing an Antipsychotic for Psychotic Depression  
2/11/202212 minutes, 33 seconds
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Neurological and Psychiatric Sequelae Due to COVID-19

COVID-19 infection is associated with new-onset neurological illness but at relatively low absolute rates. On the other hand, rates for new-onset anxiety and mood disorders can be higher, at 7% and 8%, respectively.  Faculty: Jim Phelps, M.D.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 31 Six-Month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19: A Retrospective Cohort Study Using Electronic Health Records
2/6/20228 minutes, 32 seconds
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SNRIs + Antipsychotics for Psychotic Depression

Which is the best antidepressant for combination treatment in psychotic depression? This episode includes the use of venlafaxine plus quetiapine and how to choose an antidepressant for combination treatment. Faculty: David Osser, M.D. Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 1.25 CMEs: The Psychopharmacology Algorithm for Psychotic Depression Node 2C: Combination Therapy: SNRIs + Antipsychotics  
2/1/202210 minutes, 40 seconds
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Approaches for Addressing Tobacco Use Disorder

How can we counsel patients about smoking cessation? In this interview, Dr. Joji Suzuki emphasizes the advantages of motivational interviewing and discusses some pharmacologic treatments, such as nicotine replacement therapies, varenicline, and bupropion. Guest: Joji Suzuki, M.D. Interviewer: Wegdan Rashad, M.D. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: The Clinical Guide On Tobacco Use Disorder - Interview with Joji Suzuki, M.D.  
1/27/202218 minutes, 42 seconds
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ECT the First-Choice Treatment for Psychotic Depression

This episode discusses the use of ECT for severely ill patients, including its benefits and limitations, as well as the use of ECT as a maintenance treatment. Faculty: David Osser, M.D. Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 1.25 CMEs: The Psychopharmacology Algorithm for Psychotic Depression Node 1: ECT for Severely Ill Patients
1/22/202210 minutes, 1 second
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Metabolic Characteristics of Newer Second-Generation Antipsychotics

What was the difference among antipsychotics? Over 1 year, lurasidone caused no net weight gain, whereas olanzapine caused a gain of 10 pounds. Perphenazine was associated with a 2 lb. loss vs olanzapine's 9.5 lb. gain. Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 30 Comparison of the Metabolic Characteristics of Newer Second-Generation Antipsychotics
1/17/202210 minutes, 9 seconds
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Prescribing Antipsychotics During Breastfeeding

This episode discusses first- and second-generation antipsychotics during breastfeeding, including clozapine, the only psychiatric drug nearly always contraindicated. Faculty: Lauren Osborne, M.D. Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 1 CME: Understanding the Use of Psychotropic Drugs in Lactation Antipsychotics During Breastfeeding
1/12/20229 minutes, 16 seconds
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Fluvoxamine for Treating COVID-19

How effective is fluvoxamine in patients with COVID-19? A 2-week course of full-dose fluvoxamine decreased clinical deterioration in outpatients with symptomatic COVID-19 infection. Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D.; Lorena Rodríguez, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 30 Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19
1/7/20229 minutes, 40 seconds
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Prescribing Antidepressants During Breastfeeding

Can we use antidepressants during breastfeeding? This episode discusses the use of antidepressants during breastfeeding, including SSRIs, TCAs, bupropion, and mirtazapine. Faculty: Lauren Osborne, M.D. Hosts: Jessica Diaz, M.D.; Lorena Rodríguez M.D. Learn more about our memberships here Earn 1 CME: Understanding the Use of Psychotropic Drugs in Lactation Antidepressants During Breastfeeding
1/2/202212 minutes, 7 seconds
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Treatment Strategies for Acute and Chronic Insomnia

Is it safe to use atypical antipsychotics for insomnia? Can we use benzodiazepines? This podcast features the different treatments for acute and chronic insomnia. It also addresses the differential diagnoses and some treatment options for insomnia and comorbid depressive disorders. Guest: Charles Reynolds M.D. Interviewer: Mohan Gautam D.O. Hosts: Jessica Diaz, M.D.; Lorena Rodríguez, M.D. Learn more about our memberships here Earn 0.5 CMEs: The Clinical Guide to Sleep Issues in Psychiatry - Interview with Charles F. Reynolds III, M.D.  
12/28/202118 minutes, 22 seconds
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Drug Use in Breastfeeding and Adverse Effects

When it comes to drug use while breastfeeding, what really matters is not the infant dose but the effect on the infant. This episode discusses drug use in breastfeeding, common adverse reactions, and their relationship to maternal dosing. Faculty: Lauren Osborne, M.D. Hosts: Jessica Diaz, M.D.; Lorena Rodríguez M.D. Learn more about our memberships here Earn 1 CME: Understanding the Use of Psychotropic Drugs in Lactation Drug Use in Breastfeeding and Adverse Effects
12/23/20217 minutes, 56 seconds
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Marine Omega-3 Fatty Acid Supplementation for BPD

A novel medication approach for borderline personality disorder is discussed. In this meta-analysis of fish oil for borderline personality disorder, the effect size relative to placebo was 0.54 (substantial) and for affective dysregulation was 0.74 (clinically very relevant). Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D.; Lorena Rodríguez, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 29 Marine Omega-3 Fatty Acid Supplementation for Borderline Personality Disorder: A Meta-Analysis
12/18/202111 minutes, 37 seconds
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Breastfeeding and Estimating Infant Drug Exposure

This episode discusses drug use in breastfeeding and how to estimate infant exposure with the milk-to-plasma ratio and the relative infant dose. Learn when these calculations can be helpful. Faculty: Lauren Osborne, M.D. Hosts: Jessica Diaz, M.D.; Lorena Rodríguez M.D. Learn more about our memberships here Earn 1 CME: Understanding the Use of Psychotropic Drugs in Lactation Estimating Infant Exposure
12/13/202113 minutes, 4 seconds
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A Method for Tapering Antipsychotics

When tapering antipsychotics, conceptualize the process as "finding a new minimum effective dose." This could take months, likely years. This episode features some dose examples. Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 29 A Method for Tapering Antipsychotic Treatment That May Minimize the Risk of Relapse  
12/8/202110 minutes, 34 seconds
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Management of Psychiatric Comorbidities With Alcohol Use Disorder

This episode discusses the prevalence and management of psychiatric comorbidities with alcohol use disorder. Learn some strategies for treating alcohol use disorder and comorbid depressive and anxiety disorders.  Faculty: Joji Suzuki, M.D. Hosts: Jessica Diaz, M.D., Flavio Guzman, M.D. Learn more about our memberships here Earn 1 CME: What Clinicians Need to Know About Alcohol Use Disorder Psychiatric Comorbidities With Alcohol Use Disorder: Prevalence and Management
12/3/202113 minutes, 7 seconds
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Tips for Treating Perimenopausal Depression

If your patient has perimenopausal depression, what are the treatment options? This podcast explains different treatment options, such as antidepressants, hormone therapy, and psychotherapy. It also addresses some strategies for managing vasomotor symptoms. Guest: Vivien Burt, M.D.; Interviewer: Mohan Gautam, D.O. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about our memberships here Earn 0.5 CMEs: Blue Moods and Hot Flashes: Treating Perimenopausal Depression - Interview with Vivien K. Burt, M.D., Ph.D.  
11/28/202118 minutes, 39 seconds